FAM9B and AURKAIP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM9B	AURKAIP1
Description		family with sequence similarity 9 member B	aurora kinase A interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Nucleus Nucleoplasm Chromosome Cytoplasm	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Spermatid Development Meiotic Cell Cycle	Mitochondrial Translation Positive Regulation Of Proteolysis
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Androgen levels ( 22936694) Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 28869591 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Male-pattern baldness ( 27182965 29146897) Metabolite levels ( 23823483)	Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Ulcerative colitis ( 28067908)
Interacting Genes		140 interacting genes: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BAIAP2L2 BARD1 BCL2A1 BET1 BLOC1S2 BRME1 BYSL C8orf33 CADPS CCDC106 CCDC116 CCDC198 CCDC70 CDC23 CDC37 CDC42EP4 CDCA7L CDSN CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DGUOK DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G ELOA FAM161A FAM9A FASTKD3 FCHSD2 FERD3L FNDC11 GFOD1 GOPC GPX1 GRAMD4 GSTK1 HAPSTR1 HNRNPLL IBSP ISCU JAZF1 LBX1 LIN7A LINC02363 LMNA LNX1 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MRRF MYG1 MYO15B NDE1 NDUFB10 NEBL NOL4 NOTO PAGE1 PAGE3 PHYH PIN4 POLL PPARA PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RNF8 RPL9 RSL24D1 RUBCN RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMARCB1 SMN1 SMN2 SNAP29 SNAP47 SNX20 SRRM4 STK3 SUCLA2 SURF6 SYT17 TBC1D25 TBRG4 TCEA2 TCEANC TGFBI TOM1L2 TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 WT1 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	6 interacting genes: ABHD4 AJUBA AURKA DEFB127 FAM9B GSK3A
Entrez ID		171483	54998
HPRD ID		15955	16457
Ensembl ID		ENSG00000177138	ENSG00000175756
Uniprot IDs		Q8IZU0	Q9NWT8
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		Protein Binding Mitochondrial Matrix RNA Binding	Negative Regulation Of UDP-glucose Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Regulation Of Mitochondrion Organization Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Meiotic Cell Cycle Positive Regulation Of Proteolysis Autosome Genomic Imprinting Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Cellular Response To Interleukin-3 Regulation Of Glycogen (starch) Synthase Activity Spindle Assembly Involved In Female Meiosis I Pronucleus Germinal Vesicle Chromosome Passenger Complex Mitotic Centrosome Separation Histone H3S10 Kinase Activity Axon Hillock Positive Regulation Of Oocyte Maturation Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Proximal Dendrite Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Cell Maturation N-acylphosphatidylethanolamine Metabolic Process Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Glycerophospholipid Metabolic Process Regulation Of Microtubule-based Process Phosphatidylethanolamine Acyl-chain Remodeling Alpha-catenin Binding Cardiac Left Ventricle Morphogenesis Cilium Disassembly Lysophosphatidic Acid Acyltransferase Activity Beta-catenin Destruction Complex Centrosome Separation Spindle Assembly Involved In Female Meiosis
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