OIT3 and LCE1C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OIT3	LCE1C
Description		oncoprotein induced transcript 3	late cornified envelope 1C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Cell Surface
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process	Renal System Process	Epidermis Development Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668) Low density lipoprotein cholesterol levels ( 29403010 33339817) Refractive error ( 32231278) Total cholesterol levels ( 29403010 33339817)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		15 interacting genes: ANAPC16 CRCT1 ESYT1 FBXO34 HOXA1 KRTAP11-1 LCE1C LCE1F LCE3A MEOX2 PLA2G12B TBATA TYSND1 UNC5B VAC14	75 interacting genes: ADAMTSL4 ALPP CHIC2 CHRD CRCT1 CREB5 CYSRT1 EFEMP1 EFEMP2 FBLN1 GUCD1 HOXA1 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE4A LCE5A MACO1 NECTIN2 NTAQ1 NTN4 NUTF2 ODF1 OIT3 OTX1 PLA2G10 PLAC8 PLSCR3 PLSCR4 POU4F2 PSMB1 SLC39A7 SPRED2 SPRY1 SPRY2 TGFB1 TRIM42 VASN VWC2 VWC2L
Entrez ID		170392	353133
HPRD ID		17660	13967
Ensembl ID		ENSG00000138315	ENSG00000197084
Uniprot IDs		Q8WWZ8	Q5T751
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Negative Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding Protein Binding Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Branch Elongation Of An Epithelium Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Epithelial To Mesenchymal Transition Axis Elongation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Elastic Fiber Negative Regulation Of Cellular Response To Growth Factor Stimulus Extracellular Matrix Assembly Negative Regulation Of ERK1 And ERK2 Cascade Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Cellular Response To Growth Factor Stimulus Basement Membrane
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