DFFB and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 10619428)
0

Data Source:
HPRD (in vitro, in vivo)

		DFFB	CIDEB
Description		DNA fragmentation factor subunit beta	cell death inducing DFFA like effector b
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Protein-containing Complex	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Nuclease Activity DNA Endonuclease Activity DNA Nuclease Activity Protein Binding Hydrolase Activity Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Disordered Domain Specific Binding	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity
	Biological Process	DNA Catabolic Process Apoptotic DNA Fragmentation Apoptotic Process Apoptotic Chromosome Condensation Negative Regulation Of Apoptotic DNA Fragmentation	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion
Pathways		Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494) Metabolite levels ( 23823483)	Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		4 interacting genes: APP CIDEB DFFA TOP2A	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		1677	27141
HPRD ID		03532	11981
Ensembl ID		ENSG00000169598	ENSG00000136305
Uniprot IDs		B4DZS0 O76075 Q96P72 Q96P73 Q96P74	Q9UHD4
PDB IDs		1IBX	1D4B
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Apoptotic Process Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Programmed Cell Death Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Protein-containing Complex Lipoprotein Particle Cell Death Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Deoxyribonuclease Activity Negative Regulation Of Apoptotic DNA Fragmentation Deoxyribonuclease Inhibitor Activity DNA Topoisomerase Type II (double Strand Cut, ATP-hydrolyzing) Activity Positive Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate DNA Topoisomerase Type II (double Strand Cut, ATP-hydrolyzing) Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Nuclease Activity Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Apoptotic Chromosome Condensation Lipid Droplet Fusion Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition DNA Topoisomerase Activity	Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?