BBS12 and QRFPR

		BBS12	QRFPR
Description		Bardet-Biedl syndrome 12	pyroglutamylated RFamide peptide receptor
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Cell Projection	Plasma Membrane Membrane
	Molecular Function	Protein Binding ATP Binding	G Protein-coupled Receptor Activity Neuropeptide Y Receptor Activity Protein Binding
	Biological Process	Intraciliary Transport Eating Behavior Fat Cell Differentiation Photoreceptor Cell Maintenance Negative Regulation Of Fat Cell Differentiation Stem Cell Differentiation Chaperone-mediated Protein Complex Assembly Negative Regulation Of Stem Cell Differentiation	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cellular Response To Hormone Stimulus
Pathways		BBSome-mediated cargo-targeting to cilium	Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Asthma ( 31959851) Caudate nucleus volume ( 31530798) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Metabolite levels ( 23823483) Mosquito bite size ( 28199695) Night sleep phenotypes ( 27126917)	Weight ( 34074324)
Interacting Genes		2 interacting genes: QRFPR TNIP3	4 interacting genes: BBS12 BBS7 GJA8 NTM
Entrez ID		166379	84109
HPRD ID		08759	09494
Ensembl ID		ENSG00000181004	ENSG00000186867
Uniprot IDs		Q6ZW61	F2Z3L3 Q96P65
PDB IDs			8WZ2 8ZH8
Enriched GO Terms of Interacting Partners?			Eye Development Fat Cell Differentiation Pigment Granule Aggregation In Cell Center Primary Palate Development Sensory Organ Development Gap Junction-mediated Intercellular Transport BBSome Intercellular Transport
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