DAB1 and KRTAP19-5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		DAB1	KRTAP19-5
Description		DAB adaptor protein 1	keratin associated protein 19-5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Synapse Perinuclear Region Of Cytoplasm Glutamatergic Synapse	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Signaling Adaptor Activity	Protein Binding
	Biological Process	Neuron Migration Cell Adhesion Negative Regulation Of Cell Adhesion Cell Surface Receptor Signaling Pathway Via JAK-STAT Small GTPase-mediated Signal Transduction Nervous System Development Axonogenesis Adult Walking Behavior Dendrite Development Ventral Spinal Cord Development Cerebellum Structural Organization Hippocampus Development Cerebral Cortex Cell Migration Cerebral Cortex Radially Oriented Cell Migration Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Layer Formation In Cerebral Cortex Radial Glia Guided Migration Of Purkinje Cell Central Nervous System Neuron Differentiation Cell Differentiation Neuron Differentiation Reelin-mediated Signaling Pathway Positive Regulation Of Neuron Differentiation Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Astrocyte Differentiation Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Axonogenesis Golgi Localization Regulation Of Synapse Maturation Motor Neuron Migration Lateral Motor Column Neuron Migration Radial Glia-guided Pyramidal Neuron Migration
Pathways		Reelin signalling pathway	Keratinization
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Age at first sexual intercourse ( 34211149) Alzheimer's disease progression score ( 29860282) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Bulimia nervosa ( 23568457) Cardiac troponin-I levels ( 31014085) Coronary artery disease ( 29472232) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Household income (MTAG) ( 31844048) Immune reponse to smallpox (secreted IL-10) ( 22610502) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Kawasaki disease ( 21221998) Lateral orbital frontal cortex volume ( 31530798) Logical memory (delayed recall) in normal cognition ( 29274321) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) Pubertal anthropometrics ( 23449627) Risk-taking tendency (4-domain principal component model) ( 30643258) Serum linoleic acid concentration in metabolic syndrome ( 31991592) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference ( 28552196) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		78 interacting genes: APLP1 APLP2 APP ARID5A BHLHE40 C1orf94 CDK5 CIART CLASRP CRK CRKL DAB2IP DAZAP2 ERBB2 ERBB3 FAM168A HMBOX1 HNRNPLL HYAL3 INPP5D ITGB2 ITGB3 ITGB5 ITGB7 ITSN1 JAK1 JUN KRTAP19-5 KRTAP19-7 KRTAP8-1 LDLR LGALS9B LGALS9C LNX1 LRP1 LRP2 LRP8 MAGED1 MAPK14 MBNL1 MBNL3 MYO6 NAF1 NTAQ1 PAFAH1B1 PCDH18 PIN1 PLCG1 POGZ PPIG PRR20A PTPN11 RAMAC RBFOX1 RBFOX2 RELN RHOXF2 ROR2 SERF2 SIAH1 SIRPB1 SMAP2 SNRPB SOCS6 SOCS7 SRC STRBP TCEA2 TCEANC TMTC3 TOLLIP USP53 VENTX VLDLR ZBTB32 ZC3H10 ZCCHC10 ZNF488	97 interacting genes: ANKHD1 APOBEC1 ARID5A ATN1 ATOSB ATPAF2 BHLHE40 C11orf16 CAMK2A CAMK2B CATSPER1 CCDC17 CELF5 CHRD COL8A1 CRACR2A CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRT3 DMRTB1 EFEMP2 ENKD1 ESRP1 EVX2 FAM168A GLIS2 GLYCTK GPANK1 GRINA GUCD1 HAPLN2 HGS HOXB9 HYPK INCA1 KIFC3 KPRP KRT34 KRTAP12-4 KRTAP15-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MAPK1IP1L MGAT5B MYOZ3 MYPOP OIP5 OLIG3 OXER1 P4HA3 PATZ1 PITX1 PITX2 PLSCR4 POU2AF1 PPP1R16A PRKAG3 PRPF31 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 PSMB2 PSMB4 RBPMS RBPMS2 RHOXF2 RNF38 RNF44 RTP5 RUSC1 SAXO4 SEMA3B SNRPC SOHLH1 SPMIP6 SPMIP9 TCF7L2 TEKT3 TLE5 TNIP1 TSPYL6 UBQLN2 VAC14 VEZF1 VPS37C ZBTB32 ZIC1 ZNF414
Entrez ID		1600	337972
HPRD ID		04582	11209
Ensembl ID		ENSG00000173406	ENSG00000186977
Uniprot IDs		O75553	Q3LI72
PDB IDs
Enriched GO Terms of Interacting Partners?		Reelin-mediated Signaling Pathway Receptor Complex Layer Formation In Cerebral Cortex Cellular Response To Growth Factor Stimulus Low-density Lipoprotein Particle Receptor Activity Response To Growth Factor Cell Surface Receptor Signaling Pathway Clathrin-coated Pit Enzyme-linked Receptor Protein Signaling Pathway Cargo Receptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Dendrite Development Neuron Projection Morphogenesis Very-low-density Lipoprotein Particle Receptor Activity Cell Projection Morphogenesis Endocytosis Regulation Of Macromolecule Metabolic Process Apolipoprotein Binding Hippocampus Development ErbB-3 Class Receptor Binding Positive Regulation Of Lysosomal Protein Catabolic Process Forebrain Development Regulation Of Gene Expression Cerebral Cortex Development System Development Positive Regulation Of Protein Catabolic Process In The Vacuole Negative Regulation Of Leukocyte Activation Regulation Of Macromolecule Biosynthetic Process Regulation Of Developmental Process Postsynaptic Specialization Organization Negative Regulation Of Immune System Process Ventral Spinal Cord Development Anatomical Structure Morphogenesis Regulation Of ERK1 And ERK2 Cascade Amyloid-beta Clearance Integrin-mediated Signaling Pathway Integrin Complex Cell Adhesion Mediated By Integrin Negative Regulation Of Cell Activation Regulation Of Synapse Organization Receptor Tyrosine Kinase Binding Nervous System Development Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Metabolic Process Glial Cell Development Protein Binding Regulation Of Cell Motility Regulation Of Cell Adhesion Postsynaptic Specialization Assembly Regulation Of Lysosomal Protein Catabolic Process	Protein Binding Axonemal A Tubule Inner Sheath Identical Protein Binding Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Myoblast Fate Commitment Sperm Flagellum Spinal Cord Motor Neuron Migration Proteasome Core Complex Nucleus Calcium- And Calmodulin-dependent Protein Kinase Complex Chromatin Intermediate Filament
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