KCTD7 and INO80B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KCTD7	INO80B
Description		potassium channel tetramerization domain containing 7	INO80 complex subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane	Nucleus Nucleoplasm Nucleolus Nuclear Body Ino80 Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Intracellular Potassium Ion Homeostasis Protein Homooligomerization Membrane Hyperpolarization Intracellular Glutamate Homeostasis	Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Remodeling DNA Damage Response Regulation Of Chromosome Organization Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Positive Regulation Of Telomere Maintenance In Response To DNA Damage
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Cotinine glucuronidation ( 25293881) Estimated glomerular filtration rate ( 31152163)	Appendicular lean mass ( 33097823)
Interacting Genes		44 interacting genes: ADAMTSL4 ATXN7L2 BAG4 CAPN1 CAPN2 CAPNS1 CUL3 DVL3 EFHC2 GAS2L2 GORASP2 INCA1 INO80B KAT5 KRT75 KRTAP13-3 LNX1 MDFI MEOX1 MEOX2 NIF3L1 NTAQ1 NXF1 PARVG PAX6 PIN1 PPARA PRPF18 PRR22 PSMA1 RAB4A REL TCEA2 TCEANC TERF1 TRIM2 TRIM3 UBC VEZF1 ZNF417 ZNF438 ZNF474 ZNF552 ZNF587	64 interacting genes: ABI2 BANP BOLL CARD9 CAVIN1 CCDC85B CD81 CDR2L CEP70 CSNK2B CYSRT1 DPPA4 DVL3 E2F6 FLACC1 GOLGA6L9 GPRASP3 HMBOX1 HMGXB4 HOMEZ HOXA1 HSF2BP IGFBP2 KCTD7 KRT34 KRT40 KRTAP10-8 KRTAP12-2 KRTAP19-1 KRTAP6-2 LHX4 LIMS1 LZTS2 MID2 MKRN3 MORN3 MTUS2 MYLIP NBPF19 NOTCH2NLA PICK1 PIP4K2B PLAGL2 PNMA1 PNMA2 RBM39 RIMBP3C SOX13 SSX2IP STAC3 THAP1 TLE5 TNS2 TRAF2 TRIB3 TRIM27 TSPYL2 U2AF2 UIMC1 USH1G YAF2 ZNF526 ZNF552 ZRANB1
Entrez ID		154881	83444
HPRD ID		13770	17110
Ensembl ID		ENSG00000243335	ENSG00000115274
Uniprot IDs		Q96MP8	Q9C086
PDB IDs			6HTS 7ZI4
Enriched GO Terms of Interacting Partners?		Calpain Complex Calcium-dependent Cysteine-type Endopeptidase Activity Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Somite Specification Proteolysis Involved In Protein Catabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific	Identical Protein Binding Protein Binding Intermediate Filament
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