TTC14 and SRRM2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		TTC14	SRRM2
Description		tetratricopeptide repeat domain 14	serine/arginine repetitive matrix 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding	RNA Binding MRNA Binding Protein Binding C2H2 Zinc Finger Domain Binding
	Biological Process		MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Glucose homeostasis traits ( 25524916)	Height ( 31562340) Venous thromboembolism ( 32232851)
Interacting Genes		12 interacting genes: CCDC39 CCDC85B CHERP ESS2 FRA10AC1 IK NKAP RBM39 SF3B2 SNIP1 SNW1 SRRM2	17 interacting genes: APP CEBPA CLK1 CSNK2A1 PIN1 PNN PRPF6 SNIP1 SRPK2 SRRM1 SRSF4 SUMO2 TTC14 USP7 XRN1 YWHAB YWHAG
Entrez ID		151613	23524
HPRD ID		15579	06913
Ensembl ID		ENSG00000163728	ENSG00000167978
Uniprot IDs		Q96N46	A0A140VK53 Q9UQ35
PDB IDs			5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6QDV 6ZYM 7A5P 7DVQ 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 9FMD
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Processing MRNA Metabolic Process Spliceosomal Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome RNA Metabolic Process Nuclear Speck Nucleic Acid Metabolic Process RNA Binding Nucleobase-containing Compound Metabolic Process U2-type Prespliceosome Assembly U2 SnRNP U2-type Catalytic Step 2 Spliceosome Spliceosomal Complex Assembly Nucleus Nucleoplasm	MRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Protein Catabolic Process RNA Splicing Nucleus RNA Splicing, Via Transesterification Reactions Regulation Of Macromolecule Metabolic Process RNA Metabolic Process Nuclear Speck Symbiont-mediated Disruption Of Host Cell PML Body MRNA Processing Nucleic Acid Metabolic Process RNA Binding Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Spliceosomal Complex Assembly Phosphoserine Residue Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Regulation Of RNA Splicing Spliceosomal Complex Negative Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Protein Targeting Positive Regulation Of Protein Catabolic Process Negative Regulation Of Gene Expression Presynapse Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Protein Stabilization Negative Regulation Of Macromolecule Biosynthetic Process Catalytic Step 2 Spliceosome Positive Regulation Of Protein Metabolic Process Negative Regulation Of Biosynthetic Process RNA Processing Positive Regulation Of Catabolic Process PML Body Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Negative Regulation Of Signal Transduction Nucleoplasm Regulation Of MRNA Processing
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