LRATD1 and CYGB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LRATD1	CYGB
Description		LRAT domain containing 1	cytoglobin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Cytosol Nuclear Speck Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding	Catalase Activity Peroxidase Activity Superoxide Dismutase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Antioxidant Activity Oxidoreductase Activity Oxygen Binding Heme Binding Metal Ion Binding Fatty Acid Peroxidase Activity Carbon Monoxide Binding Nitrite Reductase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor
	Biological Process	Cell Morphogenesis Cell Motility	Response To Hypoxia Response To Oxidative Stress Negative Regulation Of Fibroblast Migration Oxygen Transport Fatty Acid Oxidation Removal Of Superoxide Radicals Negative Regulation Of Collagen Biosynthetic Process Nitric Oxide Metabolic Process Nitric Oxide Catabolic Process Negative Regulation Of Hepatic Stellate Cell Activation
Pathways			eNOS activation Intracellular oxygen transport
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: ARHGEF5 CYGB	11 interacting genes: ARHGAP8 ATP13A2 CD300C DDI1 FAAP100 LRATD1 MZT1 PRR5-ARHGAP8 PRRG4 TBC1D16 WBP11
Entrez ID		151354	114757
HPRD ID		17647	06479
Ensembl ID		ENSG00000162981	ENSG00000161544
Uniprot IDs		Q96KN4	Q8WWM9
PDB IDs			1UMO 1URV 1URY 1UT0 1UX9 1V5H 2DC3 3AG0 4B3W
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Import Myeloid Dendritic Cell Chemotaxis Regulation Of Protein Import Negative Regulation Of Hepatic Stellate Cell Activation Nitric Oxide Catabolic Process Catalase Activity Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor Carbon Monoxide Binding Superoxide Dismutase Activity Nitrite Reductase Activity Positive Regulation Of Podosome Assembly Regulation Of Podosome Assembly Dendritic Cell Chemotaxis Positive Regulation Of JUN Kinase Activity Negative Regulation Of Collagen Biosynthetic Process Oxygen Carrier Activity Removal Of Superoxide Radicals Oxygen Transport Negative Regulation Of Fibroblast Migration Dendritic Cell Migration Antioxidant Activity Hematopoietic Stem Cell Homeostasis Oxygen Binding Nitric Oxide Metabolic Process Peroxidase Activity Reactive Nitrogen Species Metabolic Process Positive Regulation Of MAP Kinase Activity Podosome Regulation Of Fibroblast Migration Regulation Of Collagen Biosynthetic Process Superoxide Metabolic Process Regulation Of Collagen Metabolic Process Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Actin Filament Bundle Assembly Regulation Of MAP Kinase Activity Cellular Oxidant Detoxification Fatty Acid Oxidation Lipid Oxidation	WW Domain Binding Spermine Transmembrane Transport ABC-type Polyamine Transporter Activity Microtubule Nucleation By Interphase Microtubule Organizing Center
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