CTSE and TUBGCP2

		CTSE	TUBGCP2
Description		cathepsin E	tubulin gamma complex component 2
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GO Annotations	Cellular Component	Endosome	Spindle Pole Gamma-tubulin Complex Nucleoplasm Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Cytoplasmic Microtubule Membrane Ciliary Basal Body
	Molecular Function	Aspartic-type Endopeptidase Activity Peptidase Activity Hydrolase Activity Identical Protein Binding	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Proteolysis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration Microtubule Nucleation Brain Development Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		MHC class II antigen presentation	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS			Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)
Interacting Genes		7 interacting genes: A2M BAG6 EDN3 EMG1 INS KCNJ15 TUBGCP2	12 interacting genes: ADAM12 BNIP3 C1R CALY CEBPA CTSE H3C1 INPP5A KIF14 PCNT POLR2E UBC
Entrez ID		1510	10844
HPRD ID		00294	18245
Ensembl ID		ENSG00000196188	ENSG00000130640
Uniprot IDs		A0A7P0MPN9 B4DNU8 P14091	Q53EQ3 Q9BSJ2
PDB IDs		1TZS	6V6B 6V6S 6X0V 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 8Q62 8RX1 8VRD 8VRJ 8VRK 9H9P
Enriched GO Terms of Interacting Partners?		Signaling Receptor Binding Negative Regulation Of Innate Immune Response Protease Binding Interleukin-8 Binding Negative Regulation Of Complement Activation, Lectin Pathway Potassium Ion Transmembrane Transport Blood Vessel Diameter Maintenance Vein Smooth Muscle Contraction Endothelin B Receptor Binding Regulation Of Tube Size Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Hormone Activity Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Hormone Secretion Alpha-beta T Cell Activation Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Proteolysis Receptor Ligand Activity Negative Regulation Of Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycogen Catabolic Process Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Maintenance Of Unfolded Protein BAT3 Complex RRNA (pseudouridine) Methyltransferase Activity Nucleologenesis Regulation Of Immune System Process Potassium Ion Transport Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Positive Regulation Of Nitric Oxide Mediated Signal Transduction Positive Regulation Of Dendritic Spine Maintenance Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Systemic Arterial Blood Pressure By Endothelin Intracellular Magnesium Ion Homeostasis Negative Regulation Of Respiratory Burst Nucleolus Organization Tumor Necrosis Factor Binding Interleukin-1 Binding Negative Regulation Of Feeding Behavior Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Immune Response Regulation Of Respiratory Burst Involved In Inflammatory Response Regulation Of Glycogen Catabolic Process Internal Peptidyl-lysine Acetylation Positive Regulation Of Respiratory Burst Nitric Oxide-cGMP-mediated Signaling NK T Cell Activation RRNA Base Methylation
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