TCF23 and DRC1

		TCF23	DRC1
Description		transcription factor 23	dynein regulatory complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Euchromatin Nucleus	Extracellular Region Cytoplasm Cytosol Cytoskeleton Axonemal Dynein Complex Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Transcription Regulator Inhibitor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Positive Regulation Of Gene Expression Cell Differentiation Developmental Process Decidualization Negative Regulation Of Muscle Cell Differentiation	Regulation Of Cilium Movement Single Fertilization Determination Of Left/right Symmetry Heart Development Flagellated Sperm Motility Axoneme Assembly Cilium Organization Cilium-dependent Cell Motility Protein-containing Complex Assembly Axonemal Dynein Complex Assembly Mucociliary Clearance Sperm Flagellum Assembly
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Serum metabolite levels ( 33031748) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: DRC1 EMD FIGLA HNRNPK U2AF2	5 interacting genes: CENPO GSK3A SPATA31H1 TCF23 WDCP
Entrez ID		150921	92749
HPRD ID		18734	11312
Ensembl ID		ENSG00000163792	ENSG00000157856
Uniprot IDs		Q7RTU1	Q96MC2
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing TMEM240-body Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Poly-pyrimidine Tract Binding Spliceosomal Complex Regulation Of RNA Splicing Positive Regulation Of Low-density Lipoprotein Particle Clearance RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Commitment Complex U2AF Complex Pre-mRNA 3'-splice Site Binding Cortical Endoplasmic Reticulum Mucociliary Clearance Cadherin Binding Spindle Pole Centrosome RNA Splicing Regulation Of MRNA Metabolic Process Random Inactivation Of X Chromosome Prp19 Complex C2H2 Zinc Finger Domain Binding Axonemal Dynein Complex U2-type Prespliceosome Oocyte Development Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Sperm Flagellum Assembly Positive Regulation Of Protein Export From Nucleus Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Regulatory NcRNA-mediated Heterochromatin Formation MRNA Processing	Negative Regulation Of UDP-glucose Catabolic Process Negative Regulation Of Muscle Cell Differentiation Mis6-Sim4 Complex Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Muscle Cell Differentiation Centromere Complex Assembly Regulation Of Glycogen (starch) Synthase Activity
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