CLDN19 and CLRN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLDN19	CLRN1
Description		claudin 19	clarin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Bicellular Tight Junction Membrane Basolateral Plasma Membrane Cell Junction Paranodal Junction Schmidt-Lanterman Incisure Apical Junction Complex Perinuclear Region Of Cytoplasm Tight Junction Anchoring Junction Mesaxon	Plasma Membrane Microvillus Microtubule Cytoskeleton Membrane Lamellipodium Trans-Golgi Network Transport Vesicle Stereocilium Basal Part Of Cell Actin-based Cell Projection
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding Cell-cell Adhesion Mediator Activity Paracellular Tight Junction Channel Activity	Protein Binding
	Biological Process	Retinal Pigment Epithelium Development Cell Adhesion Visual Perception Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Neuronal Action Potential Propagation Actin Cytoskeleton Organization Negative Regulation Of Cell Migration Cell Junction Assembly Apical Junction Assembly Renal Absorption Bicellular Tight Junction Assembly Tight Junction Organization Regulation Of Transepithelial Transport Paracellular Transport	Actin Filament Organization Visual Perception Sensory Perception Of Sound Positive Regulation Of Lamellipodium Assembly Photoreceptor Cell Maintenance Cell Motility Neuromuscular Process Controlling Balance Sensory Perception Of Light Stimulus Equilibrioception Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Development
Pathways		Tight junction interactions
Drugs
Diseases			Usher syndrome (US)
GWAS			Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Chronotype ( 30696823) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)
Interacting Genes		63 interacting genes: AQP6 AQP9 BCL2L13 BIK BSCL2 BTN2A1 CD200R1 CD53 CD74 CLEC14A CLEC2D CLRN1 CREB3 CXCR3 CYSRT1 ERGIC3 FAM209A FCGR1A FCGRT FKBP7 FNDC9 GGT7 GJA8 GORAB GPR161 GPX8 HSD17B13 ICAM3 IFNGR2 IL3RA KEL KIR2DL3 KRT31 KRT34 LAPTM5 LRRC25 LRRC4C MFF MS4A14 MS4A4A MUC1 PDZK1IP1 PKD2L1 PLEKHB2 PVR SAR1A SCARB2 SGPL1 SLAMF6 SLC10A1 SLC35H1 SPACA1 SRPK2 STOM STOML3 SUSD3 SYNE4 TM4SF18 TMEM106C TMEM248 TMEM52B TMEM80 TNFSF14	29 interacting genes: ALG8 BRICD5 C2CD2L CANT1 CCL4L2 CLDN19 CTXN3 DRAM1 FAM24B FUT9 ITGAM MGST3 MLF1 NRM SEC22B SLC34A3 SLC61A1 TMEM140 TMEM147 TMEM222 TMEM239 TMEM31 TMEM50B TMEM86B TMIE TMPPE TMPRSS4 UNC50 ZDHHC15
Entrez ID		149461	7401
HPRD ID		10834	05905
Ensembl ID		ENSG00000164007	ENSG00000163646
Uniprot IDs		Q8N6F1	P58418
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding External Side Of Plasma Membrane Plasma Membrane	Membrane
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