STARD6 and RAB27B

		STARD6	RAB27B
Description		StAR related lipid transfer domain containing 6	RAB27B, member RAS oncogene family
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GO Annotations	Cellular Component		Endosome Late Endosome Golgi Apparatus Golgi Stack Plasma Membrane Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Synaptic Vesicle Membrane Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Exocytic Vesicle Axon Cytoplasm
	Molecular Function	Lipid Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Lipid Transport	Exocytosis Regulation Of Exocytosis Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport
Pathways		Pregnenolone biosynthesis	Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Psoriasis ( 23143594 25903422)	Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		1 interacting genes: RAB27B	18 interacting genes: CNPY2 DHPS EFHD1 GORASP2 MEX3C MLPH MYRIP NR2E1 RPH3A RPH3AL SEC11A STARD6 SYTL1 SYTL2 SYTL4 TUFT1 UNC13D WDR7
Entrez ID		147323	5874
HPRD ID		09518	04846
Ensembl ID		ENSG00000174448	ENSG00000041353
Uniprot IDs		A0A8I5QL07 P59095	O00194
PDB IDs		2MOU	2F7S
Enriched GO Terms of Interacting Partners?		Trans-Golgi Network Transport Vesicle Protein Transport Along Microtubule Myosin V Binding Platelet Dense Granule Membrane Zymogen Granule Membrane Anterograde Axonal Protein Transport Multivesicular Body Membrane Exocytic Vesicle Presynaptic Endocytosis Synaptic Vesicle Endocytosis Anterograde Axonal Transport Golgi Stack Multivesicular Body Sorting Pathway Protein Localization To Synapse Axon Cytoplasm Axonal Transport GDP Binding Protein Localization To Cell Junction Positive Regulation Of Exocytosis Axo-dendritic Transport G Protein Activity Vesicle-mediated Transport In Synapse Melanosome Secretory Granule Synaptic Vesicle Membrane Late Endosome Transport Along Microtubule Regulation Of Exocytosis Cytoskeleton-dependent Intracellular Transport Exocytosis Microtubule-based Transport Protein Domain Specific Binding Positive Regulation Of Secretion By Cell GTPase Activity Positive Regulation Of Secretion Apical Plasma Membrane GTP Binding Secretion By Cell Microtubule-based Movement Endocytosis	Small GTPase Binding Exocytic Vesicle Neurexin Family Protein Binding Intracellular Protein Transport Positive Regulation Of Exocytosis Exocytosis Secretion By Cell Secretion Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion Positive Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Regulation Of Exocytosis Calcium-dependent Activation Of Synaptic Vesicle Fusion Cellular Localization Protein Transport Establishment Of Localization In Cell Intracellular Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Melanosome Positive Regulation Of Vesicle Fusion Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Regulation Of Secretion By Cell Regulation Of Regulated Secretory Pathway Myosin Binding Regulation Of Secretion Positive Regulation Of Protein Secretion Regulation Of Vesicle Fusion Regulation Of Insulin Secretion Regulation Of Calcium Ion-dependent Exocytosis Deoxyhypusine Synthase Activity Forebrain Generation Of Neurons Regulation Of Peptide Hormone Secretion Positive Regulation Of Transport Transport Vesicle Membrane Intracellular Protein Localization Cytoplasmic Vesicle Cortical Actin Cytoskeleton Spermidine Catabolic Process Positive Regulation Of Protein Transport Granuloma Formation Regulation Of Vesicle-mediated Transport Zinc Ion Binding Regulation Of Hormone Secretion Regulation Of Protein Secretion Phosphatidylinositol-4,5-bisphosphate Binding Regulation Of Timing Of Neuron Differentiation Polyamine Catabolic Process Amygdala Development Structural Constituent Of Tooth Enamel
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