WIPF2 and DNMBP

Number of citations of the paper that reports this interaction (PubMedID 14506234)
0

Data Source:
HPRD (in vitro)

		WIPF2	DNMBP
Description		WAS/WASL interacting protein family member 2	dynamin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Golgi Stack Cytosol Cytoskeleton Cell-cell Junction Nuclear Body Synapse Anchoring Junction Presynapse
	Molecular Function	Actin Binding Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process		Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Cilium Assembly
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle RHOJ GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	CDC42 GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 31619474) Blond vs. brown/black hair color ( 30531825) Household income (MTAG) ( 31844048) PR interval in Tripanosoma cruzi seropositivity ( 24324551)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		13 interacting genes: APBB1 DNMBP GRB2 ITSN2 NCK2 PFN1 PTP4A2 SORBS3 TCERG1 TVP23A WAS WASL WWOX	21 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 UBC VASP WASF1 WASL WIPF2
Entrez ID		147179	23268
HPRD ID		18304	10918
Ensembl ID		ENSG00000171475	ENSG00000107554
Uniprot IDs		Q8TF74	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs			1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Supramolecular Fiber Organization Phosphotyrosine Residue Binding Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament Organization Regulation Of Actin Filament-based Process Regulation Of Actin Filament Length Positive Regulation Of Actin Filament Polymerization Vesicle Membrane Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Component Size Regulation Of Cytoskeleton Organization Positive Regulation Of Protein Polymerization Regulation Of Stress Fiber Assembly Proline-rich Region Binding Positive Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Component Organization Positive Regulation Of Transcription By RNA Polymerase II GTPase Regulator Activity Actin Filament-based Process Negative Regulation Of Stress Fiber Assembly Actin Filament Polymerization Negative Regulation Of Actin Filament Bundle Assembly Cell-cell Junction Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Organelle Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Projection Assembly Guanyl-nucleotide Exchange Factor Adaptor Activity Regulation Of T Cell Antigen Processing And Presentation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Actin Polymerization Or Depolymerization Actin Filament Organization Actin Filament-based Movement Cytosol Positive Regulation Of Actin Filament Bundle Assembly Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Plasma Membrane Bounded Cell Projection Organization Transcription Coactivator Activity Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Cell Projection Organization Regulation Of Organelle Organization T Cell Activation	Actin Filament Organization Lamellipodium Cytoskeleton Actin Polymerization Or Depolymerization Supramolecular Fiber Organization Profilin Binding Focal Adhesion Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Actin Binding Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament Organization Filopodium Neuron Projection Development Positive Regulation Of Protein Polymerization Actin Cytoskeleton Organization SH3 Domain Binding Positive Regulation Of Cellular Component Organization Postsynapse SCAR Complex Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Polymerization Actin Filament-based Process Plasma Membrane Bounded Cell Projection Organization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein-containing Complex Assembly Regulation Of Postsynapse Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cellular Component Organization Regulation Of Actin Filament Length Actin Cytoskeleton Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Component Biogenesis Cell Projection Organization Cytoplasm Rac Protein Signal Transduction Positive Regulation Of Protein-containing Complex Assembly Cytosol Positive Regulation Of Lamellipodium Assembly Axon Guidance Neuron Projection Guidance Cell Projection Regulation Of Cell Projection Assembly Actin Filament Polymerization Extracellular Exosome Positive Regulation Of Lamellipodium Organization
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