CST1 and IER3IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CST1	IER3IP1
Description		cystatin SN	immediate early response 3 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Vesicle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity	Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste	Type B Pancreatic Cell Differentiation Positive Regulation Of Extracellular Matrix Constituent Secretion Chromatin Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Brain Development Negative Regulation Of Cell Population Proliferation Gene Expression Protein Transport Organ Growth Glucose Homeostasis Negative Regulation Of Apoptotic Process Cell Maturation Positive Regulation Of Protein Secretion Insulin Metabolic Process Regulation Of Fibroblast Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Fruit consumption ( 32066663)
Interacting Genes		8 interacting genes: APOE ASPH CSNK2B IER3IP1 IRF8 SGTA SYCE1L UBQLN2	43 interacting genes: AIG1 C19orf18 CDIPT CERS2 CERS4 CSNK2B CST1 DPM3 EBP ELOVL4 ERMP1 FAM210B FCER1G GJB1 GOSR2 GPR42 HERPUD2 JAGN1 KCNA1 MOSPD3 PEX12 PIGP PLP1 POMK RGS2 SCN3B SLC30A4 TK1 TM4SF18 TMEM128 TMEM14A TMEM14B TMEM167A TMEM237 TMEM258 TMEM80 TMEM86B TMPPE TMX2 TRHR UBQLN1 YIPF4 ZFYVE27
Entrez ID		1469	51124
HPRD ID		00460	13727
Ensembl ID		ENSG00000170373	ENSG00000134049
Uniprot IDs		P01037	Q9Y5U9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Proteolysis Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Protein Catabolic Process Negative Regulation Of Cell Population Proliferation Negative Regulation Of Phospholipid Efflux Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Metabolic Process Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Negative Regulation Of Endothelial Cell Migration Regulation Of Protein Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Positive Regulation Of Protein Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Presynaptic Membrane Organization Chylomicron Remnant Lipid Transport Involved In Lipid Storage Lipoprotein Particle Regulation Of Protein Transport Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle Positive Regulation Of Protein Localization Peptidyl-aspartic Acid 3-dioxygenase Activity Plasmacytoid Dendritic Cell Differentiation TRC Complex Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Extracellular Matrix Constituent Secretion Regulation Of Establishment Of Protein Localization Positive Regulation Of Catabolic Process Intermediate-density Lipoprotein Particle	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Lipid Biosynthetic Process Sphingosine N-acyltransferase Activity Membrane Lipid Metabolic Process Lipid Metabolic Process Response To Endoplasmic Reticulum Stress
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