MGAT5B and TENT5B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MGAT5B	TENT5B
Description		alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	terminal nucleotidyltransferase 5B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding Transferase Activity Glycosyltransferase Activity Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding Metal Ion Binding	Protein Binding Transferase Activity Nucleotidyltransferase Activity Poly(A) RNA Polymerase Activity
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Positive Regulation Of Translation Negative Regulation Of Cell Cycle MRNA Stabilization
Pathways		DAG1 core M2 glycosylations
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Colorectal or endometrial cancer ( 26621817) Early cardiac repolarization ( 22683750) Nicotine dependence symptom count ( 25555482) Pulmonary emphysema ( 24383474) Refractive error ( 32231278) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)
Interacting Genes		112 interacting genes: ABHD11 ADAMTSL4 ADRA2C ANAPC11 ANTKMT ATG9A ATP23 BMF C10orf55 C17orf50 C22orf39 CAMK2B CD46 CFAP68 CFTR CIMIP2B CREB5 CSN3 CTAG1A CTAG1B CXCL5 CYSRT1 DMRT3 EIF4E2 EIF4ENIF1 FAM83A FNDC11 FOXH1 GATA1 GLYCTK GNE HIGD2B HOXA1 HOXC8 HR HSD3B7 HUNK IGLL5 IQCE IVD KCTD17 KLHL38 KPRP KRT86 KRTAP1-1 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 LASP1 LONRF1 MAGED1 MCCD1 MDFI MKRN3 MSX2 NHLRC4 OIP5 OTX1 PITX1 PLA2G10 PLSCR1 PTGER3 PTH1R PTPRZ1 R3HDM2 RBP3 RBPMS RHOXF2 RSKR RTN4R SLC16A5 SLC25A48 SMARCC1 SMUG1 SNRPC SPAG8 SSC4D STK16 SYNGAP1 TBX6 TEKT5 TENT5B TMEM42 TNS2 TRIM35 TRIM42 TRIP13 TSPAN4 TXNDC5 TYRO3 UBAP2 UNKL VAC14 ZIC1 ZNF20 ZNF414 ZNF581	61 interacting genes: ACY1 AKAP8L AKAP9 ATXN1 BHLHE40 C10orf55 C3orf36 CERCAM CIMIP2B CYSRT1 DAZAP2 ENKD1 FAM168B FOS FOSB FOXI1 HIVEP1 HMGXB4 HNRNPF KLHL38 KRT34 KRTAP19-6 KRTAP6-1 KRTAP6-2 MGAT5B MKRN3 NAF1 NICN1 NR1D2 OTX2 PLK4 POU2AF1 POU6F2 PROP1 PSMB8 PSMF1 RBPMS2 RFX6 RHOXF2 RIMBP3C RUSC1 SLC15A2 SLC27A4 SMAP2 SOHLH1 SOX5 SPAG8 TBX6 TENT5A TLE5 TNS2 TRIP13 UBAP2 UBQLN2 USP54 YPEL3 ZBTB2 ZC3H10 ZNF503 ZNF620 ZNF688
Entrez ID		146664	115572
HPRD ID		14392	16882
Ensembl ID		ENSG00000167889	ENSG00000158246
Uniprot IDs		Q3V5L5	Q96A09
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament	Identical Protein Binding DNA-binding Transcription Factor Activity DNA Binding Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Nucleus Chromatin RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process
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