DYDC1 and NME5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		DYDC1	NME5
Description		DPY30 domain containing 1	NME/NM23 family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Radial Spoke Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection Set1C/COMPASS Complex	Radial Spoke Extracellular Region Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding	Nucleoside Diphosphate Kinase Activity Protein Binding 3'-5'-DNA Exonuclease Activity Hydrolase Activity
	Biological Process		Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Spermatogenesis Spermatid Development Nucleoside Metabolic Process Ventricular System Development Cell Differentiation Spermatid Differentiation Establishment Of Localization In Cell Cilium Assembly Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708)	Atrial fibrillation ( 29892015) Autism spectrum disorder or schizophrenia ( 28540026) Carboplatin disposition in epthelial ovarian cancer ( 29367611)
Interacting Genes		34 interacting genes: ARNT2 CCHCR1 CCNC CEP57L1 DPY30 ENKD1 GHITM HDAC4 HGS KRT75 LMO2 LNX1 MID2 MOS NME5 PDZD4 PIK3R2 PKN1 POU6F2 PPP2R5D PSMA1 TCHP TEAD4 TFPT TLE5 TSGA10IP TXLNB TXNDC9 USHBP1 USP2 VPS37C VPS9D1 WAC ZGPAT	4 interacting genes: CEP76 DYDC1 DYDC2 ZYX
Entrez ID		143241	8382
HPRD ID		14062	04655
Ensembl ID		ENSG00000170788	ENSG00000112981
Uniprot IDs		Q8WWB3	A0A0S2Z4L9 P56597
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?			Set1C/COMPASS Complex
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