CRYBA2 and CRYBB1

Number of citations of the paper that reports this interaction (PubMedID 17662718)
29

Data Source:
HPRD (two hybrid)

		CRYBA2	CRYBB1
Description		crystallin beta A2	crystallin beta B1
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding	Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Lens Development In Camera-type Eye Visual Perception	Lens Development In Camera-type Eye Visual Perception
Pathways
Drugs
Diseases
GWAS		Height ( 18391951 31562340) Macular thickness ( 30535121) Neutrophil percentage of white cells ( 32888494) Systolic blood pressure ( 28234671) Type 2 diabetes (adjusted for BMI) ( 30297969)	Metabolite levels ( 23823483)
Interacting Genes		27 interacting genes: ANAPC11 ARID5A BPIFA1 C10orf55 C22orf39 CALCOCO1 CCDC33 CRYBB1 CRYBB2 CRYBB3 CTDSP1 CYSRT1 FHL3 FHL5 KRTAP11-1 KRTAP13-3 KRTAP7-1 LASP1 NFKBID OXER1 PRR22 RUSC1 TRAF2 TRIP13 UNKL VAC14 YPEL3	10 interacting genes: ABCC8 AP1B1 CRYBA1 CRYBA2 CRYBA4 DDIT4L DRC4 EXOC5 TERF1 TERF2IP
Entrez ID		1412	1414
HPRD ID		02905	09021
Ensembl ID		ENSG00000163499	ENSG00000100122
Uniprot IDs		P53672	P53674
PDB IDs			1OKI
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Eye Lens Lens Development In Camera-type Eye	Structural Constituent Of Eye Lens Lens Development In Camera-type Eye Shelterin Complex Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Visual Perception Sensory Perception Of Light Stimulus Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Positive Regulation Of Uterine Smooth Muscle Relaxation Negative Regulation Of Neuroblast Migration Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Secretion By Cell Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Nervous System Process Sulfonylurea Receptor Activity Positive Regulation Of Telomere Maintenance DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Telomere Maintenance Potassium Ion-transporting ATPase Complex Positive Regulation Of Relaxation Of Smooth Muscle Negative Regulation Of Blood-brain Barrier Permeability Glutamate Secretion, Neurotransmission Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Sensory Perception Inward Rectifying Potassium Channel Positive Regulation Of Tight Junction Disassembly Telomere Organization Negative Regulation Of DNA Metabolic Process Secretion Basolateral Protein Secretion Negative Regulation Of Establishment Of Protein Localization Positive Regulation Of Protein Localization To Cilium ATP-activated Inward Rectifier Potassium Channel Activity Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Anoikis Regulation Of Establishment Of Protein Localization To Chromosome
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