CARNMT1 and -

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CARNMT1	-
Description		carnosine N-methyltransferase 1	U2 small nuclear RNA auxiliary factor 1 like 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Transferase Activity Carnosine N-methyltransferase Activity Protein Homodimerization Activity
	Biological Process	L-histidine Catabolic Process Methylation Carnosine Metabolic Process
Pathways		Histidine catabolism
Drugs
Diseases
GWAS			HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		3 interacting genes: - APP U2AF1	16 interacting genes: AP1B1 AP2B1 CARNMT1 EFHC2 HMGB2 HNRNPK KRT1 KRT75 MEOX2 MLH1 SNRNP35 SRRM4 SRSF3 TRA2B U2AF2 ZNF417
Entrez ID		138199	102724594
HPRD ID		12958
Ensembl ID		ENSG00000156017	ENSG00000275895
Uniprot IDs		Q8N4J0
PDB IDs		5YF0 5YF1 5YF2
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Pre-mRNA 3'-splice Site Binding RS Domain Binding U2AF Complex Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing RNA Splicing MRNA Metabolic Process MRNA Processing MRNA Binding Regulation Of MRNA Metabolic Process Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome Clathrin Adaptor Complex RNA Processing Nucleic Acid Binding Pre-mRNA Binding RNA Metabolic Process Nucleic Acid Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Binding Negative Regulation Of RNA Splicing Membrane Coat Clathrin Binding Condensed Chromosome Positive Regulation Of RNA Splicing Somatic Cell DNA Recombination Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Carnosine N-methyltransferase Activity Nucleobase-containing Compound Metabolic Process Protein Domain Specific Binding Cornified Envelope Structural Constituent Of Skin Epidermis Double-strand Break Repair Via Nonhomologous End Joining Non-sequence-specific DNA Binding, Bending Keratinization Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Protein-RNA Sequence-specific Adaptor Activity Poly-pyrimidine Tract Binding Carnosine Metabolic Process Intermediate Filament Organization Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Male Meiosis Chromosome Segregation MutLalpha Complex Keratin Filament Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization
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