GPAT4 and IDO2

		GPAT4	IDO2
Description		glycerol-3-phosphate acyltransferase 4	indoleamine 2,3-dioxygenase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cytoplasm Cytosol
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Glycerol-3-phosphate O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity Lysophosphatidic Acid Acyltransferase Activity	Tryptophan 2,3-dioxygenase Activity Protein Binding Oxidoreductase Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding Dioxygenase Activity
	Biological Process	Glandular Epithelial Cell Maturation Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Triglyceride Metabolic Process Phosphatidic Acid Biosynthetic Process Phosphatidylcholine Biosynthetic Process Lactation Lipid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process Mammary Gland Development Regulation Of Multicellular Organism Growth Diacylglycerol Metabolic Process	Immune System Process L-tryptophan Catabolic Process L-tryptophan Catabolic Process To Kynurenine 'de Novo' NAD+ Biosynthetic Process From L-tryptophan
Pathways		Synthesis of PA	Tryptophan catabolism
Drugs
Diseases
GWAS			Schizophrenia x sex interaction ( 34099189)
Interacting Genes		3 interacting genes: GFI1B HSD17B7 IDO2	7 interacting genes: BANP GINS4 GPAT4 HOOK3 LZTS1 NKX6-3 SMIM19
Entrez ID		137964	169355
HPRD ID		12175	14113
Ensembl ID		ENSG00000158669	ENSG00000188676
Uniprot IDs		Q86UL3	Q6ZQW0
PDB IDs
Enriched GO Terms of Interacting Partners?		Estrogen Biosynthetic Process 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity 5-alpha-androstane-3-beta,17-beta-diol Dehydrogenase (NADP+) Activity 'de Novo' NAD+ Biosynthetic Process From L-tryptophan Kynurenine Metabolic Process L-tryptophan Catabolic Process To Kynurenine Indoleamine 2,3-dioxygenase Activity L-tryptophan Catabolic Process Tryptophan 2,3-dioxygenase Activity Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Oxidoreductase Activity L-tryptophan Metabolic Process Androgen Metabolic Process Steroid Hormone Biosynthetic Process NAD+ Biosynthetic Process Benzene-containing Compound Metabolic Process Aromatic Amino Acid Family Catabolic Process Pyridine Nucleotide Biosynthetic Process Estrogen Metabolic Process Hormone Biosynthetic Process Cholesterol Biosynthetic Process Aromatic Amino Acid Metabolic Process Sterol Biosynthetic Process NAD+ Metabolic Process
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