CLVS2 and TBC1D32

		CLVS2	TBC1D32
Description		clavesin 2	TBC1 domain family member 32
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane	Cytoplasm Cilium Cell Projection
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-3,5-bisphosphate Binding Phosphatidylinositol Bisphosphate Binding	Protein Binding
	Biological Process	Lysosome Organization	Kidney Development Lens Development In Camera-type Eye Retinal Pigment Epithelium Development Smoothened Signaling Pathway Determination Of Left/right Symmetry Heart Development Neural Tube Patterning Neural Tube Development Embryonic Digit Morphogenesis Camera-type Eye Development Roof Of Mouth Development Retina Development In Camera-type Eye Cilium Assembly Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Non-motile Cilium Assembly
Pathways		Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Refractive error ( 32231278) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)	Peak creatinine levels in vancomycin therapy ( 26030142)
Interacting Genes		17 interacting genes: EMSY FBXW2 FLAD1 GSTM3 GSTZ1 GYS1 KAZN MEOX2 MYH7 PAFAH1B2 PCYT2 PGAM2 PHETA2 S100A7 S100A7A TACC2 TBC1D32	2 interacting genes: CLVS2 FAM184A
Entrez ID		134829	221322
HPRD ID		16666	12867
Ensembl ID		ENSG00000146352	ENSG00000146350
Uniprot IDs		Q5SYC1	Q96NH3
PDB IDs
Enriched GO Terms of Interacting Partners?		Catalytic Activity Transition Metal Ion Binding Glutathione Transferase Activity Identical Protein Binding Cytosol Maleylacetoacetate Isomerase Activity Ethanolamine-phosphate Cytidylyltransferase Activity FMN Adenylyltransferase Activity FAD Biosynthetic Process FAD Diphosphatase Activity	Phosphatidylinositol Bisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding Lysosome Organization Clathrin-coated Vesicle
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