UBLCP1 and TSC22D4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		UBLCP1	TSC22D4
Description		ubiquitin like domain containing CTD phosphatase 1	TSC22 domain family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Cytoplasm Dendrite Cell Projection Synapse
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity Metal Ion Binding Proteasome Regulatory Particle Binding	Protein Binding
	Biological Process	Negative Regulation Of ATP-dependent Activity Regulation Of Proteasome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Glucose Homeostasis Negative Regulation Of DNA-templated Transcription Neuron Cellular Homeostasis Neuron Projection Extension
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Inflammatory skin disease ( 25574825) Male-pattern baldness ( 29146897) Primary biliary cholangitis ( 26394269) Serum sulfate level ( 27412988) Tuberculosis susceptibility in HIV infection ( 26942285) Ulcerative colitis ( 28067908)	Brain morphology (MOSTest) ( 32665545) Platelet count ( 27863252) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: PAAF1 PSMC1 PSMC4 PSMC5 PSMD2 TSC22D4	61 interacting genes: ABLIM1 AIFM1 ARHGAP9 BLZF1 CBX8 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU CTNNAL1 ENKD1 FBXW7 FRMD6 FXR2 GOLGA2 GORASP2 KPNA2 KRT40 LBP LMO1 LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP MYO15B NIF3L1 NOC4L NRBP1 PCBP1 PCDH17 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 RACK1 SACS SAT1 SMAD3 SMARCB1 SYT17 TEX11 TLE5 TRIM55 TRIM63 TSC22D1 TSPOAP1 UBLCP1 VBP1 ZBTB24 ZMYND10 ZNF580
Entrez ID		134510	81628
HPRD ID		08318	18231
Ensembl ID		ENSG00000164332	ENSG00000166925
Uniprot IDs		Q8WVY7	B4DKI8 Q9Y3Q8
PDB IDs		2KX3 2LGD 2M17
Enriched GO Terms of Interacting Partners?		Proteasome Complex Proteasome Regulatory Particle, Base Subcomplex Proteasome Accessory Complex Proteasome-activating Activity Proteasome Regulatory Particle Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Macromolecule Catabolic Process ATP Hydrolysis Activity Regulation Of Proteolysis Proteolysis Positive Regulation Of Catabolic Process Nuclear Proteasome Complex Proteasome Storage Granule Regulation Of Protein Metabolic Process Thyrotropin-releasing Hormone Receptor Binding Cytosolic Proteasome Complex Positive Regulation Of Inclusion Body Assembly Positive Regulation Of Protein Metabolic Process Catabolic Process General Transcription Initiation Factor Binding Inclusion Body Transcription Factor Binding Regulation Of Inclusion Body Assembly ATP Binding Regulation Of Primary Metabolic Process TBP-class Protein Binding Protein Metabolic Process Enzyme Regulator Activity Blastocyst Development Cytosol Regulation Of Macromolecule Metabolic Process Nucleotide Binding	Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Protein Binding Organelle Organization Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Signal Transduction Cytoplasm Negative Regulation Of Protein Metabolic Process Regulation Of Protein Stability Negative Regulation Of Amyloid-beta Formation Cellular Response To Glucose Stimulus Phosphothreonine Residue Binding Cellular Response To Hydrogen Peroxide Protein Localization To Lipid Droplet Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Glucose Mediated Signaling Pathway Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Carbohydrate Stimulus Organelle Disassembly Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Regulation Of Amide Metabolic Process Protein Stabilization Regulation Of Protein Metabolic Process Viral RNA Genome Replication Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly Intracellular Glucose Homeostasis Protein Ubiquitination Identical Protein Binding Regulation Of Protein Catabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Catabolic Process Regulation Of Protein Modification Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Response To Hydrogen Peroxide Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Ubiquitin-protein Transferase Activator Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Release Of Cytochrome C From Mitochondria
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