LSM11 and SNRPB

Number of citations of the paper that reports this interaction (PubMedID 12975319)
45

Data Source:
HPRD (in vivo)

		LSM11	SNRPB
Description		LSM11, U7 small nuclear RNA associated	small nuclear ribonucleoprotein polypeptides B and B1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U7 SnRNP Telomerase Holoenzyme Complex Nuclear Body Histone Pre-mRNA 3'end Processing Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding U7 SnRNA Binding	RNA Binding Protein Binding Telomerase RNA Binding SnRNP Binding Histone Pre-mRNA DCP Binding U1 SnRNP Binding U2 SnRNP Binding
	Biological Process	MRNA Processing MRNA 3'-end Processing By Stem-loop Binding And Cleavage Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Chromatin Organization	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing Protein Methylation RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly
Pathways		SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		9 interacting genes: LSM10 MIR10B MIR128-1 MIR20A MIRLET7A1 RAB19 SMN1 SNRPB ZNF473	92 interacting genes: AKAP9 ASCC2 BAG4 BANP C10orf55 CALCOCO2 CD2BP2 CDKN2A CEP55 CLNS1A COA7 COG6 COIL CREM CTDP1 CYSRT1 DAB1 DDX20 DHX9 DMRTB1 ERG28 EXOSC8 FAM168B FBN2 FHL3 FNBP4 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GIGYF1 GIGYF2 GOLGA2 HNRNPH1 HOXA1 IL7R INCA1 KRT31 KRT34 KRT40 KRTAP19-1 KRTAP19-6 KRTAP6-1 KRTAP6-2 KRTAP6-3 L3MBTL3 LSM11 LSM8 MAGI2 MBD3L1 OIP5 OOEP PFDN5 PLEKHB2 PNMA1 PRMT5 PRMT7 PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 PSMA3 RBM12 RBPMS RFX6 SERTAD3 SKIC2 SMN1 SMN2 SMNDC1 SNRPD1 SNRPD3 SNUPN SP3 SPAG8 SS18L1 STRAP STXBP2 STXBP3 TFIP11 TOP3B TRAF4 TRIM23 UBQLN2 UBXN11 USP54 WBP4 WDR77 WWP2 ZNF143
Entrez ID		134353	6628
HPRD ID		11289	01655
Ensembl ID		ENSG00000155858	ENSG00000125835
Uniprot IDs		P83369	P14678 Q66K91
PDB IDs		6V4X 8G1U	1D3B 3CW1 3JCR 3PGW 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9FMD 9GBW 9GC0 9GCL
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Regulatory NcRNA-mediated Gene Silencing Histone Pre-mRNA DCP Binding Negative Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis MRNA 3'-end Processing By Stem-loop Binding And Cleavage Cajal Body U7 SnRNP MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration SMN-Sm Protein Complex MRNA 3'-UTR Binding Regulation Of Translation MRNA Processing Positive Regulation Of MRNA Metabolic Process Histone MRNA Metabolic Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of MRNA Stability Regulation Of Endothelial Cell Migration MRNA 3'-end Processing Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Negative Regulation Of Blood Vessel Endothelial Cell Migration Cytoplasmic U SnRNP Body Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Lipoprotein Transport Negative Regulation Of Cardioblast Proliferation RNA Processing Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Endothelial Cell Migration RNA Splicing Negative Regulation Of Locomotion RNA 3'-end Processing Extracellular Vesicle U2 SnRNP Binding Regulation Of Cell Migration	Spliceosomal SnRNP Assembly SMN-Sm Protein Complex SMN Complex Protein-RNA Complex Assembly Gemini Of Cajal Bodies RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome Methylosome Nuclear Body RNA Metabolic Process RNA Binding Nucleus Protein-containing Complex Assembly Protein Binding Protein-containing Complex Organization Nucleic Acid Metabolic Process Cajal Body Nucleoplasm Intermediate Filament PICln-Sm Protein Complex DNA-templated Transcription Termination Precatalytic Spliceosome Spliceosomal Complex Assembly Spliceosomal Complex Cytosol Ribonucleoprotein Complex Binding U4/U6 X U5 Tri-snRNP Complex Small Nuclear Ribonucleoprotein Complex U7 SnRNA Binding Tertiary Granule Protein-arginine Omega-N Symmetric Methyltransferase Activity Nucleobase-containing Compound Metabolic Process Identical Protein Binding U2-type Precatalytic Spliceosome U5 SnRNP Presynaptic Dense Core Vesicle Exocytosis Commitment Complex Histone H4R3 Methyltransferase Activity Peptidyl-arginine Methylation Spliceosomal Tri-snRNP Complex Neuronal Dense Core Vesicle Exocytosis Methyl-CpG Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing 3'-5' RNA Helicase Activity U7 SnRNP
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