FAM168B and WDR25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM168B	WDR25
Description		family with sequence similarity 168 member B	WD repeat domain 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Axon Cell Projection Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS			Menarche (age at onset) ( 25231870 27182965) Refractive error ( 32231278) Walking pace ( 33128006)
Interacting Genes		52 interacting genes: AGXT ARID5A BAG3 CAMK2A CCNK CSTF2 CSTF2T EGLN3 FAM168A FAM222B FOXH1 FOXI1 GLIS2 GPS2 HOXB9 HSF4 KRTAP26-1 LASP1 MED25 MSRB3 MYOZ3 NEDD9 OTX1 PATZ1 PITX1 POGZ POM121 PRR35 RAMAC RBFOX2 RHOXF2 ROR2 SAMD7 SAXO4 SNRPB SNRPC SPAG8 TCF7L2 TENT5B TIAL1 TLE5 TLX3 TUBA3D UBAP2 VENTX VEZF1 VGLL3 VPS37C WDR25 YPEL3 ZC3H10 ZIC1	32 interacting genes: ACTMAP AKAP8L BCL11B CNFN CYSRT1 DVL3 FAM168B FHL3 FOXI1 GOLGA6L9 HSF2BP KRT31 KRT34 KRT40 KRTAP12-3 KRTAP15-1 KRTAP3-1 KRTAP6-3 LDOC1 LNX1 MKRN3 NBPF19 NOTCH2NLA NOTCH3 PFDN5 PNMA1 PRDM14 PSME3 TEPSIN TRIM23 UBXN11 ZNF34
Entrez ID		130074	79446
HPRD ID		17295	14649
Ensembl ID		ENSG00000152102	ENSG00000176473
Uniprot IDs		A1KXE4	A0A384NPW5 Q64LD2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Nucleoplasm Sequence-specific Double-stranded DNA Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Myoblast Fate Commitment Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process DNA Binding DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Positive Regulation Of Protein Localization To Nucleus Chromatin Transcription Corepressor Activity Protein Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Inner Ear Morphogenesis Transcription Regulator Complex MRNA Cleavage And Polyadenylation Specificity Factor Complex Transcription Cis-regulatory Region Binding U2-type Prespliceosome Negative Regulation Of Androgen Receptor Signaling Pathway Nuclear Retinoid X Receptor Binding Regulation Of Protein Localization To Nucleus U1 SnRNP Embryonic Morphogenesis	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Structural Molecule Activity Intermediate Filament Organization
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