TSACC and DTNB

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TSACC	DTNB
Description		TSSK6 activating cochaperone	dystrobrevin beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Plasma Membrane Basal Plasma Membrane Postsynaptic Density Membrane Dendrite Cell Projection Synapse Inhibitory Synapse Postsynapse
	Molecular Function	Protein Binding Protein-folding Chaperone Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process		Neuron Differentiation Synaptic Signaling
Pathways			Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149)	A body shape index ( 34021172) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cutaneous malignant melanoma ( 32341527) Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Height ( 18391951) Heschl's gyrus morphology ( 25130324) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) LDL cholesterol ( 21347282) Macular thickness ( 30535121) Multiple myeloma ( 26007630 22120009 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Nevus count or cutaneous melanoma ( 32341527) Resistant hypertension ( 31545351) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 28552196 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Working memory ( 31598132)
Interacting Genes		4 interacting genes: DTNB FOXP2 KDM1A LIX1	61 interacting genes: ABI1 ABI2 ABI3 AMOTL2 BEGAIN CBY2 CCDC136 CCDC196 CCDC85B CCDC88B CCHCR1 CEP55 CEP63 CTBP2 DEUP1 DMD DTNBP1 FAM167A FSD2 GGA1 HMG20A KIF5A KIF5B KRT15 KRT27 KRT31 KRT33B KRT35 KRT38 KRT40 LURAP1 MB21D2 MTUS2 NDEL1 NUP62 PICK1 POU6F2 PPFIA1 PPFIBP2 PPP1R13B PRKAR1B PRTFDC1 SNCA SNTA1 SNTG1 SNTG2 SPZ1 SSBP3 TFIP11 TRAF2 TRIM27 TRIM37 TRIM54 TSACC TXLNA USHBP1 UTRN VCP VPS52 ZBTB9 ZRANB1
Entrez ID		128229	1838
HPRD ID		10252	09091
Ensembl ID		ENSG00000163467	ENSG00000138101
Uniprot IDs		Q96A04 V9GYT6	B7Z202 B7Z6A9 E7EVB6 E9PEY4 O60941 Q1I0L3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebral Cortex Development Putamen Development Caudate Nucleus Development Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Response To Fungicide MRF Binding Histone H3K4 Demethylase Activity Guanine Metabolic Process Protein Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Righting Reflex Vocal Learning Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Observational Learning Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Neuron Differentiation Histone H3K9 Demethylase Activity Positive Regulation Of Cell Size Cerebellar Purkinje Cell Differentiation Inhibitory Synapse DNA Repair Complex Auditory Behavior Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Mechanosensory Behavior Purine Nucleobase Metabolic Process Histone Demethylase Activity Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Reflex Cell Differentiation In Hindbrain Vocalization Behavior Smooth Muscle Tissue Development Nuclear Androgen Receptor Binding Positive Regulation Of Neuroblast Proliferation Telomeric DNA Binding Histone Methyltransferase Complex Regulation Of Chromatin Organization Cellular Response To Gamma Radiation DNA Repair-dependent Chromatin Remodeling Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Mesenchymal Cell Proliferation Neuron Maturation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of Androgen Receptor Signaling Pathway Regulation Of Mesenchymal Cell Proliferation	Cytoskeleton Syntrophin Complex Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Dystrophin-associated Glycoprotein Complex Cytoskeleton Organization Intermediate Filament Organization Supramolecular Fiber Organization Keratin Filament Organelle Organization Intermediate Filament Actin-based Cell Projection Protein Binding SCAR Complex Synaptic Vesicle Transport Vesicle Transport Along Microtubule Cytosol Microtubule Binding Establishment Of Vesicle Localization Sarcolemma Vesicle Cytoskeletal Trafficking Retrograde Axonal Transport Axon Cytoplasm Vesicle Localization Cytoplasm Axonal Transport Epithelial Cell Differentiation Identical Protein Binding Cytosolic Transport Microtubule-based Process Retrograde Neuronal Dense Core Vesicle Transport De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Morphogenesis Of An Epithelium Centriole Assembly Aggresome Assembly Signaling Adaptor Activity Mitotic Centrosome Separation De Novo Centriole Assembly Filopodium Axo-dendritic Transport Intracellular Transport Negative Regulation Of Cytoskeleton Organization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Organelle Transport Along Microtubule Stress Granule Disassembly Regulation Of Actin Nucleation Regulation Of Sodium Ion Transmembrane Transport Actin Binding
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