DNAH14 and MIXL1

		DNAH14	MIXL1
Description		dynein axonemal heavy chain 14	Mix paired-like homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Microtubule Cilium Dynein Complex Cell Projection 9+2 Motile Cilium	Chromatin Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Microtubule-based Movement Cilium Movement Involved In Cell Motility	Endoderm Formation Hematopoietic Progenitor Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Gastrulation Endoderm Development Heart Development Hemopoiesis Cell Differentiation Endodermal Cell Differentiation Cell Migration Involved In Gastrulation Positive Regulation Of Transcription By RNA Polymerase II Digestive Tract Development Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Mesoderm Development
Pathways			Germ layer formation at gastrulation Formation of definitive endoderm
Drugs
Diseases
GWAS		Adult body size ( 32376654) Copper levels ( 26025379) Delirium ( 29631748) Feeling nervous ( 29500382) Femur bone mineral density x serum urate levels interaction ( 34046847) Gut microbiota relative abundance (Bifidobacterium) ( 33208821) Heel bone mineral density x serum urate levels interaction ( 34046847) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
Interacting Genes		8 interacting genes: ACBD3 APP CNIH3 ENAH FBXO7 MIXL1 SDE2 TMEM63A	1 interacting genes: DNAH14
Entrez ID		127602	83881
HPRD ID		19478	10086
Ensembl ID		ENSG00000185842	ENSG00000185155
Uniprot IDs		A0A804HLD3 M9MMK7 Q0VDD8	Q9H2W2
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Dendritic Shaft Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Cell Cycle G1/S Phase Transition Glial Cytoplasmic Inclusion Classical Lewy Body Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Lewy Body Corona Lewy Neurite Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Regulation Of Mitotic Cell Cycle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Surfactant Secretion Lewy Body Core Positive Regulation Of Mesoderm Development Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Osmolarity-sensing Monoatomic Cation Channel Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Hemopoiesis Regulation Of Toll Signaling Pathway	Dynein Intermediate Chain Binding 9+2 Motile Cilium Minus-end-directed Microtubule Motor Activity Dynein Light Intermediate Chain Binding Dynein Complex Cilium Movement Involved In Cell Motility Cilium Movement Microtubule Microtubule-based Movement
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