NR2C2AP and SLC16A3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NR2C2AP	SLC16A3
Description		nuclear receptor 2C2 associated protein	solute carrier family 16 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Nuclear Membrane Apical Part Of Cell
	Molecular Function	Protein Binding	RNA Binding Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Lactate:proton Symporter Activity Transmembrane Transporter Activity Pyruvate Transmembrane Transporter Activity
	Biological Process		Monocarboxylic Acid Transport Lactate Transport Lactate Transmembrane Transport Plasma Membrane Lactate Transport Pyruvate Catabolic Process Transmembrane Transport Pyruvate Transmembrane Transport
Pathways		Nuclear Receptor transcription pathway	Basigin interactions Proton-coupled monocarboxylate transport
Drugs			Pyruvic acid
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756)	Hemoglobin ( 32888494) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: BCL2L13 CILP2 DDIT4L NR2C2 REL SLC16A3 TCF4 TEPSIN VPS52	10 interacting genes: BANP BSG CDC42 FAM9B GJA8 HDAC7 HPCA NR2C2AP UBQLN1 UBQLN2
Entrez ID		126382	9123
HPRD ID		16376	04854
Ensembl ID		ENSG00000184162	ENSG00000141526
Uniprot IDs		Q86WQ0	O15427
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Transport GBD Domain Binding Storage Vacuole Regulation Of Endocytosis Regulation Of Receptor Internalization Regulation Of Transmembrane Transporter Activity Response To Ketamine Regulation Of Monoatomic Ion Transmembrane Transporter Activity Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Store-operated Calcium Channel Activity Positive Regulation Of Matrix Metallopeptidase Secretion Endothelin Receptor Signaling Pathway Involved In Heart Process Kinase Binding Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Endothelial Cell Migration Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Identical Protein Binding Response To Aroclor 1254 Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of Proteasomal Protein Catabolic Process
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