MBD3L2 and TRIML2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MBD3L2	TRIML2
Description		methyl-CpG binding domain protein 3 like 2	tripartite motif family like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm
	Molecular Function	Protein Binding Methyl-CpG Binding	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation Regulation Of Transcription By RNA Polymerase II Regulation Of Chromatin Organization	Protein Ubiquitination Response To Retinoic Acid Innate Immune Response
Pathways
Drugs
Diseases
GWAS			Polycystic ovary syndrome ( 25574032)
Interacting Genes		12 interacting genes: CCDC136 GOLGA6L9 GPRASP2 KRT27 KRT34 KRTAP6-3 MBD2 MDFI POLD3 RUNDC3A SBK3 TRIML2	46 interacting genes: ABI2 BLOC1S2 CBY2 CCDC146 CCHCR1 CCNH CDR2 CTBP2 EIF2B1 EIF3M FAM90A1 FAM9C HGS ING5 ITGB3BP KRT15 KRT24 KRT27 KRT31 KRT34 KRT38 KRT75 MBD3L2 MBD3L3 MEOX1 MEOX2 NECAB2 NFKBID NUP62 PICK1 POLR1H POU6F2 SH2D4A STN1 SUMO2 SYCE2 TBC1D25 TCF4 TFIP11 TRIM54 TSEN54 TSG101 USHBP1 XAF1 ZBED1 ZFHX3
Entrez ID		125997	205860
HPRD ID		12139	08696
Ensembl ID		ENSG00000230522	ENSG00000179046
Uniprot IDs		Q8NHZ7	A0A804HJA0 B7ZLC3 Q8N7C3
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Protein Binding Supramolecular Fiber Organization Somite Specification Epithelial Cell Differentiation Cytoskeleton Morphogenesis Of An Epithelium Cytoskeleton Organization Organelle Organization Cellular Developmental Process Tissue Morphogenesis Segment Specification Somite Development Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion
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