TBC1D16 and CYGB

		TBC1D16	CYGB
Description		TBC1 domain family member 16	cytoglobin
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Cytosol	Nucleus Cytoplasm Cytosol Nuclear Speck Neuron Projection Neuronal Cell Body
	Molecular Function	GTPase Activator Activity Protein Binding	Catalase Activity Peroxidase Activity Superoxide Dismutase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Antioxidant Activity Oxidoreductase Activity Oxygen Binding Heme Binding Metal Ion Binding Fatty Acid Peroxidase Activity Carbon Monoxide Binding Nitrite Reductase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor
	Biological Process	Regulation Of Receptor Recycling Regulation Of Cilium Assembly	Response To Hypoxia Response To Oxidative Stress Negative Regulation Of Fibroblast Migration Oxygen Transport Fatty Acid Oxidation Removal Of Superoxide Radicals Negative Regulation Of Collagen Biosynthetic Process Nitric Oxide Metabolic Process Nitric Oxide Catabolic Process Negative Regulation Of Hepatic Stellate Cell Activation
Pathways		TBC/RABGAPs	eNOS activation Intracellular oxygen transport
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Hematology traits ( 30576415) Mean reticulocyte volume ( 32888494) Non-albumin protein levels ( 29403010) Serum total protein levels ( 29403010)
Interacting Genes		16 interacting genes: CYGB GABARAPL1 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP5-9 MAP1LC3A NOTCH2NLA PSMA3 RGS17 RGS20 TNS2 TRAF1	11 interacting genes: ARHGAP8 ATP13A2 CD300C DDI1 FAAP100 LRATD1 MZT1 PRR5-ARHGAP8 PRRG4 TBC1D16 WBP11
Entrez ID		125058	114757
HPRD ID		10261	06479
Ensembl ID		ENSG00000167291	ENSG00000161544
Uniprot IDs		Q8TBP0	Q8WWM9
PDB IDs			1UMO 1URV 1URY 1UT0 1UX9 1V5H 2DC3 3AG0 4B3W
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding Cytosol Autophagosome Maturation Fatty Acid Peroxidase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor Autophagosome Membrane Mitophagy Negative Regulation Of Hepatic Stellate Cell Activation Nitric Oxide Catabolic Process Autophagy Of Mitochondrion Autophagosome Catalase Activity Carbon Monoxide Binding	WW Domain Binding Spermine Transmembrane Transport ABC-type Polyamine Transporter Activity Microtubule Nucleation By Interphase Microtubule Organizing Center
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