GGT6 and GRINA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GGT6	GRINA
Description		gamma-glutamyltransferase 6	glutamate ionotropic receptor NMDA type subunit associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Membrane
	Molecular Function	Protein Binding Transferase Activity Acyltransferase Activity Hydrolase Activity Glutathione Hydrolase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity	Calcium Channel Activity Protein Binding Transmembrane Transporter Binding
	Biological Process	Glutathione Metabolic Process Glutathione Biosynthetic Process Leukotriene D4 Biosynthetic Process	Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Neuron Apoptotic Process Calcium Ion Transmembrane Transport Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Glutathione synthesis and recycling Aflatoxin activation and detoxification Paracetamol ADME
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 28107422) LDL cholesterol ( 25961943) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010)
Interacting Genes		11 interacting genes: ADAM33 BMP10 ENTPD3 FAIM2 FAM3C GRINA NOTCH3 PIGS SEC22A TMBIM1 TNMD	9 interacting genes: DRD2 FMO1 GGT6 GLP1R GPX8 KRTAP19-5 KRTAP6-2 TIAL1 TMEM242
Entrez ID		124975	2907
HPRD ID		08293	15927
Ensembl ID		ENSG00000167741	ENSG00000178719
Uniprot IDs		B4DKN3 B4DPG6 J3KPJ0 Q6P531 Q6ZPD7	Q7Z429
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Calcium Channel Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Calcium Ion Transmembrane Transport Golgi Membrane Regulation Of Neuron Apoptotic Process Negative Regulation Of Apoptotic Signaling Pathway Calcium Ion Transport Apoptotic Signaling Pathway Negative Regulation Of Fas Signaling Pathway Apyrase Activity Regulation Of Apoptotic Signaling Pathway Endoplasmic Reticulum Cerebellar Granular Layer Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?