RHEBL1 and DRC2

		RHEBL1	DRC2
Description		RHEB like 1	dynein regulatory complex subunit 2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane	Cytoplasm Cytoskeleton Axonemal Dynein Complex Cilium Axoneme Motile Cilium Ciliary Basal Body Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding	Protein Binding
	Biological Process	Signal Transduction Small GTPase-mediated Signal Transduction TOR Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity	Regulation Of Cilium Movement Cilium Assembly Cilium-dependent Cell Motility Axonemal Dynein Complex Assembly
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744 31043756 33263727) Reaction time ( 29844566)
Interacting Genes		14 interacting genes: ACVR1 AKT1 APPL1 BMPR1B DRC2 EIF4EBP1 FHL3 MTOR PRKAB2 SMAD1 SMAD2 SMAD4 TGFBR1 TXNL4A	4 interacting genes: DNAJC22 ENO1 FAM186B RHEBL1
Entrez ID		121268	85478
HPRD ID		15245	14867
Ensembl ID		ENSG00000167550	ENSG00000139537
Uniprot IDs		Q8TAI7	B4DXQ7 Q8IXS2
PDB IDs		3OES	8J07
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Response To Growth Factor Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway SMAD Binding I-SMAD Binding Cellular Response To Growth Factor Stimulus Positive Regulation Of Epithelial To Mesenchymal Transition Cell Fate Commitment Transforming Growth Factor Beta Receptor Activity, Type I Activin Receptor Signaling Pathway SMAD Protein Complex Regulation Of Epithelial To Mesenchymal Transition Heteromeric SMAD Protein Complex Osteoblast Differentiation Ameboidal-type Cell Migration Positive Regulation Of Multicellular Organismal Process Transmembrane Receptor Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Differentiation Pattern Specification Process BMP Signaling Pathway Homomeric SMAD Protein Complex SMAD Protein Signal Transduction Positive Regulation Of Gene Expression Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regionalization Cellular Response To BMP Stimulus Activin Responsive Factor Complex Positive Regulation Of Developmental Process Animal Organ Development Ventricular Septum Morphogenesis Cell Surface Receptor Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Translational Initiation Gastrulation Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Differentiation Regulation Of Multicellular Organismal Process Protein Serine/threonine Kinase Activity Heart Valve Morphogenesis Tissue Development Mesoderm Development Activin Receptor Complex Activin Receptor Activity, Type I Trophoblast Cell Migration Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Embryonic Pattern Specification BMP Receptor Activity
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