CLNS1A and SNRPD1

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, biochemical, two hybrid, two hybrid)

		CLNS1A	SNRPD1
Description		chloride nucleotide-sensitive channel 1A	small nuclear ribonucleoprotein D1 polypeptide
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Methylosome PICln-Sm Protein Complex	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding U1 SnRNP Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Processing Chloride Transport Cell Volume Homeostasis RNA Splicing MRNA Cis Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing 7-methylguanosine Cap Hypermethylation U2-type Prespliceosome Assembly
Pathways		snRNP Assembly	snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Platelet distribution width ( 32888494) Tourette syndrome ( 30818990)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		15 interacting genes: ACTB ALK CSNK2A1 EIF4A2 EPB41 EPB41L3 FRMD7 ITGA2B LARP1 LSM10 PRMT5 SNRPB SNRPD1 UBC WDR77	19 interacting genes: CEBPA CLNS1A DDX20 ERCC6 FOXP1 GEMIN2 GEMIN4 GEMIN5 IL7R LSM8 PRMT5 PTEN SMN1 SMN2 SNRPB SNRPD2 SREK1 U2AF1 WDR77
Entrez ID		1207	6632
HPRD ID		03694	03040
Ensembl ID		ENSG00000074201	ENSG00000167088
Uniprot IDs		E9PJF4 E9PMI6 J3KN38 P54105	P62314
PDB IDs		6V0O 9E3A 9E3B	1B34 3CW1 3JCR 3PGW 4F7U 4PJO 4V98 4WZJ 5MQF 5O9Z 5XJC 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7B0Y 7DVQ 7EVO 7QTT 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8R7N 8RC0 8RM5 8RO2 8Y6O 8Y7E 9E3B 9E3C 9FMD 9GBW 9GC0 9GCL
Enriched GO Terms of Interacting Partners?		Methylosome Spliceosomal SnRNP Assembly Histone Pre-mRNA DCP Binding U7 SnRNP U1 SnRNP Binding Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Regulation Of Dopamine Receptor Signaling Pathway U4 SnRNP Structural Constituent Of Cytoskeleton Small Nuclear Ribonucleoprotein Complex Regulation Of Translational Initiation SMN-Sm Protein Complex Macromolecule Methylation U1 SnRNP U5 SnRNP Cytosol U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Regulation Of Protein Localization To Cell Periphery Cortical Cytoskeleton Ribonucleoprotein Complex Cortical Actin Cytoskeleton Organization U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U2 SnRNP Methyl-CpG Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Methylation U4/U6 X U5 Tri-snRNP Complex Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Response To Environmental Enrichment Negative Regulation Of Translational Initiation Negative Regulation Of RNA-dependent RNA Polymerase Activity Cortical Cytoskeleton Organization Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome Methylation Positive Regulation Of RNA Splicing Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Oocyte Axis Specification Cytoplasmic U SnRNP Body RNA Binding Protein Metabolic Process MRNA Metabolic Process Regulation Of Norepinephrine Uptake Swimming Behavior Cytoskeletal Protein Binding U2 SnRNP Binding	Spliceosomal SnRNP Assembly SMN-Sm Protein Complex Protein-RNA Complex Assembly RNA Splicing SMN Complex Gemini Of Cajal Bodies MRNA Processing RNA Metabolic Process MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleoplasm Methylosome RNA Processing Nucleic Acid Metabolic Process Spliceosomal Complex Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly Macromolecule Metabolic Process Protein-containing Complex Assembly Protein-containing Complex Organization MRNA Splicing, Via Spliceosome Nuclear Body Nucleus Small Nuclear Ribonucleoprotein Complex Cajal Body Cellular Component Assembly DNA-templated Transcription Termination Positive Regulation Of MRNA Splicing, Via Spliceosome U4/U6 X U5 Tri-snRNP Complex RNA Binding Positive Regulation Of RNA Splicing PICln-Sm Protein Complex U2-type Precatalytic Spliceosome 7-methylguanosine Cap Hypermethylation Endothelial Cell Activation U4 SnRNP Regulation Of Cell Size Catalytic Step 2 Spliceosome U1 SnRNP Precatalytic Spliceosome Positive Regulation Of Gene Expression U5 SnRNP Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Methylation U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Methyl-CpG Binding Regulation Of MRNA Processing U2-type Spliceosomal Complex
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