ZFYVE27 and GIMAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFYVE27	GIMAP1
Description		zinc finger FYVE-type containing 27	GTPase, IMAP family member 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endomembrane System Membrane Axon Dendrite Growth Cone Membrane Cell Projection Recycling Endosome Membrane Endoplasmic Reticulum Tubular Network	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Axon Extension Neurotrophin TRK Receptor Signaling Pathway Endoplasmic Reticulum Tubular Network Formation Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		18 interacting genes: APP GIMAP1 GIMAP5 IER3IP1 ORMDL1 OTOP3 PIP4P2 SACM1L SEC22A SLC30A8 SLC66A2 STX7 TMEM128 TMEM14C TMEM243 TMEM65 TSPAN2 YIF1A	40 interacting genes: AQP6 ARL13B BLCAP CD79A CLEC10A CPLX4 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCGR2A GJA8 GPX8 HSD17B11 IL3RA JAGN1 MGST3 PTGES REEP4 RMDN3 SCN3B SLC10A6 SLC14A1 SLC18A1 SLC71A2 STOM STX1A THAP4 TM4SF19 TMEM101 TMEM14B TMEM35A TMEM45B TMEM79 TMX1 TMX2 ZDHHC15 ZFYVE27
Entrez ID		118813	170575
HPRD ID		15735	16278
Ensembl ID		ENSG00000155256	ENSG00000213203
Uniprot IDs		A0A0S2Z5V0 A0A0S2Z627 B7Z6J9 Q5T4F4	A0A090N8Z4 Q8WWP7
PDB IDs		1X4U	3V70
Enriched GO Terms of Interacting Partners?		Membrane Microglia Development Intracellular Transport Vesicle-mediated Transport Insulin Metabolic Process Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Phosphatidylinositol Dephosphorylation Cellular Localization Endoplasmic Reticulum Establishment Of Localization In Cell SNAP Receptor Activity Golgi Membrane Endoplasmic Reticulum Membrane COPII-coated ER To Golgi Transport Vesicle Phospholipid Dephosphorylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Endosome Amylin Binding Positive Regulation Of Toll Signaling Pathway	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Glutathione Peroxidase Activity Protein Binding Disulfide Oxidoreductase Activity
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