SSX2IP and POLL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SSX2IP	POLL
Description		SSX family member 2 interacting protein	DNA polymerase lambda
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytoskeleton Adherens Junction Cell Leading Edge Protein-containing Complex Centriolar Satellite Ciliary Basal Body Cell Projection Anchoring Junction	Nucleus Nucleoplasm Chromosome Site Of Double-strand Break
	Molecular Function	Protein Binding Protein Domain Specific Binding	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity Lyase Activity DNA Polymerase Activity Metal Ion Binding 5'-deoxyribose-5-phosphate Lyase Activity
	Biological Process	Centrosome Cycle Cell Adhesion Cell Projection Organization Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Regulation Of Cell Motility	Double-strand Break Repair Via Homologous Recombination DNA Replication DNA Repair Base-excision Repair, Gap-filling Nucleotide-excision Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Damage Response Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process
Pathways			Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS		Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		114 interacting genes: ABLIM3 ACTN1 ACTN2 AEN AFDN AP1M1 ARNT2 ATOSA BCL6 BEX2 BKGD BRCA1 BYSL CARD9 CCDC187 CCDC198 CCHCR1 CCNH CDC23 CDC42 CDCA7L CHCHD3 DAXX DRG1 DVL2 EAF2 EHHADH EIF4A2 ERAL1 FAM124B FAM161A FANCG FANCL FBF1 FNDC11 FRMD6 GEM GOLGA2 GOLGA8F GRAP2 HDAC4 HNRNPLL IKBKG INO80B KAT5 KDM1A KIF9 KIFC3 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MCM7 MFAP1 MORN4 MOS MRPL53 NAA10 NDN NIF3L1 NOL12 NTAQ1 PHC2 PIMREG PKN1 PNMA1 POLL PRKAA1 PRKAB2 PRMT6 PRPF3 PRPF31 PSMA1 RAB1A RNF6 SCNM1 SHFL SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TRIM42 TRIM54 TSGA10IP TSTD2 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZFYVE26 ZGPAT ZMAT2 ZNF124 ZNF202 ZNF250 ZNF3 ZNF408 ZNF417 ZNF438 ZNF587 ZNF648 ZNF688 ZNF71 ZNF792 ZRSR2 ZSCAN12	42 interacting genes: APP ATM CCNDBP1 CDK1 CDK2 CMTM5 FAM9B FSD2 GOLGA6L9 HMBOX1 HUWE1 KRT16 KRT19 KRT27 KRT40 KRTAP10-3 KRTAP10-7 LCN2 LDOC1 MAGEA12 MAGEA2 MAGEA2B MAL2 MCC MDFI PCNA PICK1 PNMA1 PRKD3 REV1 RPA1 SSX2IP TFCP2 TFIP11 TNFRSF10D TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H ZRANB1
Entrez ID		117178	27343
HPRD ID		10566	09394
Ensembl ID		ENSG00000117155	ENSG00000166169
Uniprot IDs		B7ZB07 Q9Y2D8	A8K860 B4DE17 Q5JQP8 Q9UGP5
PDB IDs			1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6 4K4G 4K4H 4K4I 4X5V 4XA5 4XQ8 4XRH 4XUS 5CA7 5CB1 5CHG 5CJ7 5CP2 5CR0 5CWR 5DDM 5DDY 5DKW 5III 5IIJ 5IIK 5IIL 5IIM 5IIN 5IIO 5W4G 7M07 7M08 7M09 7M0A 7M0B 7M0C 7M0D 7M0E 7M43 7M44 7M45 7M46 7M47 7M48 7M49 7M4A 7M4B 7M4C 7M4D 7M4E 7M4F 7M4G 7M4H 7M4I 7M4J 7M4K 7M4L 7UN7 8U0O
Enriched GO Terms of Interacting Partners?		Nucleus Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Zinc Ion Binding Nucleoplasm Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Nuclear Androgen Receptor Binding Metal Ion Binding Regulation Of Metabolic Process DNA Damage Response DNA Recombination DNA-binding Transcription Factor Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Spliceosomal Complex Mitotic Spindle U2-type Precatalytic Spliceosome Keratin Filament MRNA Splicing, Via Spliceosome DNA Binding RNA Splicing, Via Transesterification Reactions Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleic Acid Metabolic Process AMP-activated Protein Kinase Activity Transcription Coactivator Activity Protein K6-linked Ubiquitination	Ubiquitin Conjugating Enzyme Activity Telomere Maintenance Chromosome, Telomeric Region Keratin Filament Protein K48-linked Ubiquitination Telomere Organization Ubiquitin-protein Transferase Activity DNA Biosynthetic Process Intermediate Filament Post-translational Protein Modification Protein Polyubiquitination Nucleus DNA Metabolic Process Protein Monoubiquitination Structural Constituent Of Skin Epidermis Cellular Senescence Cyclin-dependent Protein Kinase Activity Chromosome Organization DNA Repair DNA Replication Intermediate Filament Organization Protein Localization To Site Of Double-strand Break Negative Regulation Of Protein Acetylation Negative Regulation Of Transcription By RNA Polymerase II Protein Modification Process Histone Kinase Activity Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process DNA Damage Response Protein Ubiquitination Protection From Non-homologous End Joining At Telomere Cellular Response To Reactive Oxygen Species Positive Regulation Of DNA Replication Positive Regulation Of Protein Ubiquitination PML Body Cyclin-dependent Protein Kinase Holoenzyme Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification By Small Protein Conjugation Cellular Response To X-ray Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus Positive Regulation Of Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Epithelial Cell Differentiation Modification-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Protein Binding DNA Strand Resection Involved In Replication Fork Processing Telomere Maintenance In Response To DNA Damage
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