DCD and IL24

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DCD	IL24
Description		dermcidin	interleukin 24
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Extrinsic Component Of Membrane Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	RNA Binding Monoatomic Ion Channel Activity Monoatomic Anion Channel Activity Protein Binding Peptidase Activity Lipid Binding Hydrolase Activity Metal Ion Binding	Cytokine Activity Protein Binding
	Biological Process	Proteolysis Inorganic Anion Transport Killing Of Cells Of Another Organism Monoatomic Ion Transmembrane Transport Defense Response To Bacterium Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Fungus Killing By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Monoatomic Anion Transmembrane Transport	Apoptotic Process Immune Response Signal Transduction Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Migration Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-4
Pathways		Antimicrobial peptides	Interleukin-20 family signaling
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Type 2 diabetes ( 18372903)	Inflammatory bowel disease ( 23128233)
Interacting Genes		8 interacting genes: APPBP2 ASPH CEBPA FOXP1 HSP90AA1 IL24 SUMO2 USP7	28 interacting genes: AKT1 APC ATM BAG4 CASP8 CCR5 CLU DCD ESR2 FBXW7 HMMR HRAS IL20RA KRAS LSP1 NOTCH2 PALB2 PARP1 PIK3CA PTEN RAD51 RARG RB1CC1 RIPK3 S100A6 S100P SMAD4 UBE3A
Entrez ID		117159	11009
HPRD ID		07363	04995
Ensembl ID		ENSG00000161634	ENSG00000162892
Uniprot IDs		P81605	Q13007
PDB IDs		2KSG 2NDK 2YMK 6SHK	6DF3 6GG1
Enriched GO Terms of Interacting Partners?		Regulation Of Proteolysis Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Muscle System Process Regulation Of Intracellular Transport Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding CTP Binding DATP Binding Regulation Of Protein Stability Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Cardiac Muscle Contraction Positive Regulation Of Intracellular Protein Transport Regulation Of Striated Muscle Contraction Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Tumor Necrosis Factor Cellular Response To Cytokine Stimulus Response To Vitamin B2 C/EBP Complex Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding Positive Regulation Of Interleukin-21 Production Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Telomere Maintenance PML Body Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Metabolic Process Regulation Of Cellular Localization CHOP-C/EBP Complex Response To Tumor Necrosis Factor Positive Regulation Of Proteasomal Protein Catabolic Process Rho GDP-dissociation Inhibitor Binding Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Establishment Of Protein Localization Transmembrane Transporter Binding Positive Regulation Of Intracellular Transport Regulation Of System Process Response To Peptide Histone Deacetylase Binding Response To Cytokine Positive Regulation Of Proteolysis Involved In Protein Catabolic Process White Fat Cell Proliferation Regulation Of Intracellular Protein Transport	Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Neuron Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Signal Transduction Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Gland Development Intracellular Signal Transduction Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Protein-containing Complex Binding Negative Regulation Of Programmed Cell Death Animal Organ Development Response To Lipid Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Apoptotic Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Identical Protein Binding Response To Gamma Radiation Myelin Maintenance Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Intracellular Signal Transduction Protein-containing Complex Regulation Of Multicellular Organismal Process Regulation Of Apoptotic Signaling Pathway Regulation Of Biological Quality Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Defense Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Response To Radiation
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