SNAP47 and TRIM59

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNAP47	TRIM59
Description		synaptosome associated protein 47	tripartite motif containing 59
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane BLOC-1 Complex SNARE Complex Synapse Perinuclear Region Of Cytoplasm Presynapse	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intraciliary Transport Particle B
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Exocytosis Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane	Protein Ubiquitination Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Host-mediated Suppression Of Symbiont Invasion
Pathways
Drugs
Diseases
GWAS		Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Night sleep phenotypes ( 27126917) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Alanine aminotransferase levels ( 33547301) Alcohol use disorder (total score) ( 30336701) Aspartate aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		23 interacting genes: APOC2 APOC4 AQP2 CEP57L1 F11R FAM9B FATE1 GOLGA2 KASH5 KLC3 LIME1 LRRC4C MAGEA6 MGST3 MID2 PVR RNF170 SAR1A SPAG5 STX1A STX1B STX4 TRIM59	31 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KEAP1 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM OTOL1 PIN1 PKNOX1 PLLP PPM1L RASSF3 RHOU SEC22A SNAP47 SYVN1 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22
Entrez ID		116841	286827
HPRD ID		17148	15568
Ensembl ID		ENSG00000143740	ENSG00000213186
Uniprot IDs		A0A087X0B7 Q5SQN1	Q8IWR1
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Binding SNAP Receptor Activity SNARE Complex Microtubule Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming SNARE Complex Assembly SNARE Binding Vesicle Docking Ciliary Rootlet Organelle Localization By Membrane Tethering Very-low-density Lipoprotein Particle Positive Regulation Of Neurotransmitter Secretion Organelle Localization Schaffer Collateral - CA1 Synapse Membrane Docking Neurotransmitter Transport Vesicle Fusion Organelle Membrane Fusion High-density Lipoprotein Particle Host-mediated Suppression Of Symbiont Invasion Presynaptic Active Zone Membrane Organelle Fusion Vesicle Organization Positive Regulation Of Excitatory Postsynaptic Potential Calcium-ion Regulated Exocytosis Positive Regulation Of Synaptic Transmission Synaptic Vesicle Exocytosis Acylglycerol Homeostasis Triglyceride Homeostasis Spindle Organization Vesicle Docking Involved In Exocytosis Myosin Head/neck Binding Membrane Fusion Sphingomyelin Phosphodiesterase Activator Activity Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Identical Protein Binding Intracellular Protein Localization Positive Regulation Of Regulated Secretory Pathway Modulation Of Excitatory Postsynaptic Potential Protein Localization To Cytoskeleton Germ Cell Development Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Lumenal Side Of Membrane Glycerol Transmembrane Transporter Activity Susceptibility To T Cell Mediated Cytotoxicity Exocytosis Positive Regulation Of Eosinophil Degranulation	Nuclear Estrogen Receptor Activity SNAP Receptor Activity Negative Regulation Of Response To Oxidative Stress
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?