CNTROB and DUSP29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CNTROB	DUSP29
Description		centrobin, centriole duplication and spindle assembly protein	dual specificity phosphatase 29
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Basal Body	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Phosphatase Activity MAP Kinase Phosphatase Activity Protein Homodimerization Activity
	Biological Process	Centriole Replication Centrosome Separation Cell Division Regulation Of Cilium Assembly Mitotic Cytokinetic Process	Protein Dephosphorylation Glucose Homeostasis Muscle Cell Differentiation Negative Regulation Of MAPK Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		23 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A HPCAL4 KRABD2 LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23 USP43	25 interacting genes: AATK ARPC3 ASPA C17orf75 CNTROB DDIT4L EPHA2 ERBB3 GOLGA6A IGF1R LMTK2 LNX1 NIF3L1 NOC4L PICK1 POLR2G PSMB5 PTK7 RNF40 ROR1 ROR2 SRSF11 STX11 TCF4 TEPSIN
Entrez ID		116840	338599
HPRD ID		13991	16846
Ensembl ID		ENSG00000170037	ENSG00000188716
Uniprot IDs		Q8N137	Q68J44
PDB IDs			2Y96
Enriched GO Terms of Interacting Partners?		Polynucleotide 3'-phosphatase Activity DNA Metabolic Process DNA Repair Positive Regulation Of DNA Repair Damaged DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair DNA Damage Response Positive Regulation Of DNA Metabolic Process Cellular Response To Stress DAPK1-calmodulin Complex Macromolecule Metabolic Process Positive Regulation Of Autophagic Cell Death Negative Regulation Of UDP-glucose Catabolic Process Regulation Of Glycogen Metabolic Process Regulation Of TOR Signaling Regulation Of Glycogen Biosynthetic Process Response To Insulin Regulation Of Double-strand Break Repair Memory T Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Pantetheine-phosphate Adenylyltransferase Activity	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Kinase Activity Protein Tyrosine Kinase Activity Receptor Complex Kinase Activity Glial Cell Development Dendritic Spine Maintenance Coreceptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transferase Activity ATP Binding
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