LYPD1 and PLSCR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LYPD1	PLSCR2
Description		LY6/PLAUR domain containing 1	phospholipid scramblase 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Side Of Membrane	Nucleus Nucleoplasm Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding Acetylcholine Receptor Inhibitor Activity Acetylcholine Receptor Binding	Calcium Ion Binding Protein Binding Phospholipid Scramblase Activity Metal Ion Binding
	Biological Process	Behavioral Fear Response Synaptic Transmission, Cholinergic Response To Nicotine Protein Localization To Plasma Membrane Acetylcholine Receptor Signaling Pathway Negative Regulation Of Protein Localization To Plasma Membrane	Plasma Membrane Phospholipid Scrambling
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Hip circumference ( 28552196)
Interacting Genes		1 interacting genes: PLSCR2	16 interacting genes: AQP1 BSND COQ9 EP300 FAM221B GNG13 HOXA1 LCE1A LCE3A LCE3E LCE5A LYPD1 OTX1 POU4F2 PSMD8 TMEM132D
Entrez ID		116372	57047
HPRD ID		14333	09621
Ensembl ID		ENSG00000150551	ENSG00000163746
Uniprot IDs		Q8N2G4	Q9NRY7
PDB IDs		6ZSS
Enriched GO Terms of Interacting Partners?		Phospholipid Translocation Phospholipid Scramblase Activity Lipid Translocation Regulation Of Membrane Lipid Distribution Plasma Membrane Phospholipid Scrambling Phospholipid Transport Plasma Membrane Organization Organophosphate Ester Transport	Keratinization Tissue Development Epidermis Development Sensory Perception Nervous System Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Behavioral Defense Response Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Sensory Perception Of Sound Sensory Perception Of Mechanical Stimulus Semicircular Canal Formation Diencephalon Morphogenesis Isoprenoid Binding Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion System Process Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Abducens Nerve Formation Optokinetic Behavior P53 Binding
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