PNMA5 and POLR3C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PNMA5	POLR3C
Description		PNMA family member 5	RNA polymerase III subunit C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	DNA Binding Single-stranded DNA Binding DNA-directed RNA Polymerase Activity Protein Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Immune System Process DNA-templated Transcription Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways			Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS
Interacting Genes		59 interacting genes: AP1M1 APPL1 ARPC4 CADPS CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 CRACR2A CSTPP1 CTNNA3 DDX6 DRC4 DZIP1L EHHADH FOXH1 FSD2 GLIPR2 GOLGA6L9 GORASP2 GPRASP3 GRB2 GYS1 HOOK3 HSF2BP KIF9 KIFC3 KPNA2 LHX3 LNX1 MAGED1 MOAP1 MYO15B NTAQ1 PAX5 PNKP PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 SORBS3 SPG21 TBC1D22B TCEA2 TCEANC TNPO2 TTC23 TXNL4B UBASH3A VIM VPS28 ZBTB25 ZFYVE26 ZMYND19 ZRANB1	38 interacting genes: ANKRD23 APP CAMK2B CEP44 CEP63 COIL DISC1 ENKD1 GOLGA2 GTF3C4 HAUS1 INCA1 KATNBL1 KIAA0408 KLHL2 KPNA1 KPNA3 KPNA5 KPNA6 KRT75 LZTS1 NCKIPSD OGT PAX6 PICK1 PNMA5 POU6F2 PRDM16 RBBP8NL ROCK1 ROPN1 SP100 TNR TRAF2 TRIM27 UBXN1 VAX1 VRTN
Entrez ID		114824	10623
HPRD ID		06678	17880
Ensembl ID		ENSG00000198883	ENSG00000186141
Uniprot IDs		Q96PV4	Q9BUI4
PDB IDs			2XUB 2XV4 5AFQ 7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		XPC Complex Cytoskeleton Protein Binding Cytoplasm	NLS-dependent Protein Nuclear Import Complex Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding NLS-bearing Protein Import Into Nucleus Spindle Pole Regulation Of Synapse Organization Microtubule-based Process Regulation Of Postsynapse Organization Negative Regulation Of Catabolic Process Regulation Of Synapse Maturation Viral Penetration Into Host Nucleus Microtubule Organizing Center Organization Cytoskeleton Organization Microtubule Cytoskeleton Organization Identical Protein Binding Protein Localization To Organelle Regulation Of Synaptic Plasticity Plasma Membrane Bounded Cell Projection Organization Intracellular Transport Of Virus Regulation Of Neuroblast Proliferation Protein Import Into Nucleus Cytoplasm Centrosome Cycle Import Into Nucleus Host Cell Regulation Of Supramolecular Fiber Organization Cytoskeleton Postsynaptic Density Nucleoplasm Regulation Of Cell Junction Assembly Central Nervous System Development Membraneless Organelle Assembly Negative Regulation Of Neuroblast Proliferation Arp2/3 Complex Binding Regulation Of Synapse Assembly Centriole Cell Projection Organization Regulation Of Cellular Component Organization Negative Regulation Of Viral Transcription Negative Regulation Of Protein Ubiquitination Cytosol Organelle Organization Protein Localization To Nucleus Modulation Of Chemical Synaptic Transmission Positive Regulation Of Multicellular Organismal Process Regulation Of Amyloid-beta Clearance Organelle Assembly Regulation Of Viral Transcription TOR Signaling Chromatin DNA Binding
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