EFHC1 and KCNJ5-AS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EFHC1	KCNJ5-AS1
Description		EF-hand domain containing 1	KCNJ5 antisense RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Spindle Cytoskeleton Axonemal Microtubule Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Neuronal Cell Body Mitotic Spindle Axonemal A Tubule Inner Sheath	Extracellular Region
	Molecular Function	Calcium Ion Binding Protein Binding Alpha-tubulin Binding	Protein Binding
	Biological Process	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Flagellated Sperm Motility Regulation Of Cell Division Cilium-dependent Cell Motility
Pathways
Drugs
Diseases		Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Atopic march ( 26542096) Clozapine-induced myocarditis in schizophrenia ( 32066683) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245) White blood cell count ( 32888494)
Interacting Genes		68 interacting genes: AKT1 CACNA1E CALCOCO2 CFAP161 CHCHD3 CIMIP1 DOK7 EFHC2 EIF4ENIF1 FMR1 GADD45B GAS2L2 GOLGA2 HOMER3 IHO1 IKZF3 IMP3 ITGB3BP KCNJ5-AS1 KCTD4 KRT15 KRT18 KRT75 LMO2 LRRC61 MAMDC2 MBD3L1 METTL27 MIIP MRNIP MTFR1L NQO2 NRIP3 NUP54 OIP5 PAX6 PBX1 PBX2 PMF1 PRR5L RCN1 REL RIMBP3 RNF125 SAPCD1 SELENOV SH3GLB2 SLAIN1 SNAI1 SORBS3 SPATA2 SYNGAP1 TCF4 TEKT1 TEX11 TLE5 TP53BP2 TRAF2 TRIP6 TRPM2 TSGA10IP TTC23L UBAP2 VBP1 WASF1 WHRN YJU2B ZBED1	7 interacting genes: APP EFHC1 FBXO44 FRS3 GPSM3 PLEKHF2 TLX3
Entrez ID		114327	219833
HPRD ID		10583	11344
Ensembl ID		ENSG00000096093	ENSG00000174370
Uniprot IDs		B2CKC5 Q5JVL4
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Protein Binding	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Central Nervous System Development Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Positive Regulation Of Chemotaxis Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Positive Regulation Of Leukocyte Chemotaxis Lipoprotein Particle Growth Factor Receptor Binding Main Axon Positive Regulation Of Leukocyte Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Early Endosome Membrane Regulation Of Chemotaxis Heparan Sulfate Binding Signaling Receptor Activator Activity
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