SGF29 and SYCE3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SGF29	SYCE3
Description		SAGA complex associated factor 29	synaptonemal complex central element protein 3
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm SAGA-type Complex Mitotic Spindle ATAC Complex	Central Element Nucleus Chromosome
	Molecular Function	Protein Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity Methylation-dependent Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Regulation Of RNA Splicing Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Chromatin	Apoptotic Process Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Spermatogenesis Ectopic Germ Cell Programmed Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Developmental Process Cell Division Meiotic Cell Cycle Positive Regulation Of Reproductive Process
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	Meiotic synapsis
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		27 interacting genes: C20orf202 CCDC102B CCDC158 CLHC1 DBF4B H3-4 KRT13 KRT15 KRT16 KRT19 KRT24 KRT33B LNX1 LZTS1 MED11 MED4 MYF5 PROSER3 RINT1 SYCE3 SYNPO TADA3 TCF4 TEX12 TFIP11 TMEM219 TRAF3IP1	7 interacting genes: BLOC1S6 HAUS1 INPP1 KRT79 PKN1 SGF29 TRIM54
Entrez ID		112869	644186
HPRD ID		13996
Ensembl ID		ENSG00000176476	ENSG00000217442
Uniprot IDs		Q96ES7	A1L190
PDB IDs		3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M	6H86
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Tissue Morphogenesis Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Central Element Supramolecular Fiber Organization Hair Cycle Protein-DNA Complex Assembly Synaptonemal Complex Assembly Structural Constituent Of Cytoskeleton Synaptonemal Complex Organization Core Mediator Complex Organelle Organization Anatomical Structure Morphogenesis Protein Binding Spine Apparatus Assembly Mediator Complex	Inositol-1,3,4-trisphosphate 1-phosphatase Activity Inositol-1,4-bisphosphate 1-phosphatase Activity Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle
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