RNF24 and UQCRH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RNF24	UQCRH
Description		ring finger protein 24	ubiquinol-cytochrome c reductase hinge protein
Image
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex III Respiratory Chain Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Quinol-cytochrome-c Reductase Activity
	Biological Process		Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Cellular Respiration Proton Transmembrane Transport
Pathways			Respiratory electron transport Complex III assembly Complex III assembly
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Nevirapine-induced hypersensitivity in HIV (drug-induced liver injury) ( 28062682) PR interval ( 32439900) Response to antidepressants in depression ( 27622933) Triglyceride levels in HIV infection ( 33109212)	Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		17 interacting genes: ABHD5 ARMC1 BNIP3 CNIH1 GOLT1A LHFPL3 NKG7 NRSN1 NT5E PLP1 SLC10A6 SLC71A2 TIMMDC1 TMX2 TRPC6 UQCRH VAMP1	7 interacting genes: ARL8A ENTREP3 NDFIP1 NDFIP2 NPM1 PRRG1 RNF24
Entrez ID		11237	7388
HPRD ID		10198	15629
Ensembl ID		ENSG00000101236	ENSG00000173660
Uniprot IDs		Q9Y225	P07919 Q567R0
PDB IDs		2EP4	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Membrane Granzyme-mediated Programmed Cell Death Signaling Pathway	WW Domain Binding Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Regulation Of Post-translational Protein Modification Regulation Of MRNA Stability Involved In Cellular Response To UV Regulation Of EIF2 Alpha Phosphorylation By DsRNA Positive Regulation Of Protein Modification Process Intracellular Transport Regulation Of Endoribonuclease Activity Negative Regulation Of Protein Transport Negative Regulation Of Isotype Switching To IgE Isotypes Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Regulation Of Ribonuclease Activity Cellular Localization Regulation Of Protein Modification Process Positive Regulation Of Centrosome Duplication Establishment Of Localization In Cell Membrane Golgi Membrane Negative Regulation Of Establishment Of Protein Localization Vacuolar Transport Negative Regulation Of Isotype Switching Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Protein Localization To Nucleolus Ribosomal Small Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Granular Component Endosome Negative Regulation Of Interleukin-4 Production Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Localization Positive Regulation Of Canonical NF-kappaB Signal Transduction CD4-positive, Alpha-beta T Cell Proliferation Tat Protein Binding Regulation Of Protein Localization To Nucleolus Regulation Of Protein Localization Ribosomal Subunit Export From Nucleus Negative Regulation Of Centrosome Duplication Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of Immunoglobulin Production Spindle Pole Centrosome Ribosomal Large Subunit Binding Endosome Membrane Alpha-beta T Cell Proliferation Regulation Of Isotype Switching To IgG Isotypes Negative Regulation Of Type 2 Immune Response
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