CORO1A and MAGOH

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CORO1A	MAGOH
Description		coronin 1A	mago homolog, exon junction complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Phagocytic Cup Nucleus Cytoplasm Early Endosome Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell-cell Junction Cell Cortex Actin Cytoskeleton Membrane Lamellipodium Axon Phagocytic Vesicle Membrane Cortical Actin Cytoskeleton Cell Leading Edge Cytoplasmic Vesicle Protein-containing Complex Synapse Phagocytic Vesicle Extracellular Exosome Glutamatergic Synapse	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome Exon-exon Junction Subcomplex Mago-y14
	Molecular Function	RNA Binding Actin Binding Actin Monomer Binding Protein Binding Cytoskeletal Protein Binding Myosin Heavy Chain Binding Identical Protein Binding Protein Homodimerization Activity Phosphatidylinositol 3-kinase Binding Actin Filament Binding	RNA Binding Protein Binding
	Biological Process	Immunological Synapse Formation Phagolysosome Assembly Calcium Ion Transport Vesicle Fusion Phagocytosis Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cell Shape Epithelial Cell Migration Cell Migration Actin Cytoskeleton Organization Leukocyte Chemotaxis Regulation Of Actin Filament Polymerization Negative Regulation Of Vesicle Fusion Cell-substrate Adhesion Uropod Organization Regulation Of Actin Cytoskeleton Organization Response To Cytokine Nerve Growth Factor Signaling Pathway T Cell Proliferation Positive Regulation Of T Cell Proliferation T Cell Activation T Cell Homeostasis Natural Killer Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Homeostasis Of Number Of Cells Within A Tissue Positive Regulation Of T Cell Activation Positive Chemotaxis Negative Regulation Of Actin Nucleation Negative Regulation Of Cellular Component Organization Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Neuron Apoptotic Process Establishment Of Localization In Cell Early Endosome To Recycling Endosome Transport Cellular Response To Interleukin-4 T Cell Migration Thymocyte Migration Positive Regulation Of T Cell Migration	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing MRNA Export From Nucleus Regulation Of Translation RNA Splicing Regulation Of MRNA Processing MRNA Transport Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Pathways		Prevention of phagosomal-lysosomal fusion	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hodgkin's lymphoma ( 30194254) Tonsillectomy ( 27182965 28928442)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		21 interacting genes: ACTB CEBPA FHL3 FSD2 FXR1 GIT2 GOLGA2 IFT20 LMO2 MAGEA11 MAGOH NCF4 POLR1C POT1 SMAD3 SMARCD1 SPATA20 STAT3 TAB1 THBS1 YTHDC1	23 interacting genes: ALYREF B4GALT2 CEP70 CORO1A CPSF7 DPH2 DPPA4 EIF4A3 FXR1 GOLGA2 IPO13 MAP1B NXF1 PPP1R16B PTBP2 RBM8A TADA2A TFIP11 UPF3B XIST YWHAQ ZKSCAN8 ZRANB1
Entrez ID		11151	4116
HPRD ID		05414	04005
Ensembl ID		ENSG00000102879	ENSG00000162385
Uniprot IDs		P31146	P61326
PDB IDs			1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 7A5P 7W59 7W5A 7W5B 7ZNJ 8C6J 8I0W 9FMD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Brahma Complex NBAF Complex RSC-type Complex NpBAF Complex GBAF Complex Positive Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase I Chromatin DNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Interleukin-6-mediated Signaling Pathway DNA-binding Transcription Factor Binding Osteoblast Development DEAD/H-box RNA Helicase Binding Nuclear Glucocorticoid Receptor Binding Transcription Regulator Complex Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transforming Growth Factor Beta Production Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nucleotide-excision Repair Negative Regulation Of Developmental Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Double-strand Break Repair Nucleoplasm Nuclear Matrix SWI/SNF Complex Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Developmental Process Positive Regulation Of Cell Differentiation Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macrophage Activation Positive Regulation Of Gene Expression Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process BHLH Transcription Factor Binding Positive Regulation Of Extracellular Matrix Organization Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Metabolic Process MRNA Transport RNA Transport Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Positive Regulation Of Metabolic Process Regulation Of G0 To G1 Transition Regulation Of Multicellular Organismal Development Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Cell Activation Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B	MRNA Binding MRNA Transport Exon-exon Junction Complex Nucleic Acid Binding RNA Transport Nucleobase-containing Compound Transport MRNA Export From Nucleus Spliceosomal Complex RNA Export From Nucleus Catalytic Step 2 Spliceosome MRNA Metabolic Process Nuclear Transport Nucleocytoplasmic Transport Nuclear Speck Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Processing Nuclear Export Cellular Localization RNA Binding Intracellular Transport Neuronal Cell Body RNA Splicing U2-type Catalytic Step 1 Spliceosome Transcription Export Complex Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nucleus Nuclear-transcribed MRNA Catabolic Process Establishment Of Localization In Cell MRNA Catabolic Process RNA Processing Regulation Of MRNA Metabolic Process Induction Of Synaptic Plasticity By Chemical Substance Ribonucleoprotein Complex Binding Positive Regulation Of Translation Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion RNA Metabolic Process Regulation Of RNA Splicing Regulation Of Translation RNA Catabolic Process Organelle Assembly MRNA Splicing, Via Spliceosome 2-(3-amino-3-carboxypropyl)histidine Synthase Complex 2-(3-amino-3-carboxypropyl)histidine Synthase Activity Uropod Organization Spliceosomal Complex Disassembly RNA Splicing, Via Transesterification Reactions Dendrite
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