CD160 and GPR89B

		CD160	GPR89B
Description		CD160 molecule	G protein-coupled receptor 89B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Side Of Membrane	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane Monoatomic Ion Channel Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Kinase Binding MHC Class I Protein Complex Binding MHC Class I Receptor Activity MHC Class Ib Receptor Activity Activating MHC Class I Receptor Activity	Protein Binding Voltage-gated Monoatomic Anion Channel Activity
	Biological Process	Angiogenesis Positive Regulation Of Cytokine Production Adaptive Immune Response Immune System Process Mucosal Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Natural Killer Cell Cytokine Production Regulation Of Adaptive Immune Response Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Negative Regulation Of Angiogenesis T Cell Costimulation Positive Regulation Of Type II Interferon Production Positive Regulation Of Natural Killer Cell Degranulation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Gram-negative Bacterium Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of Adaptive Immune Memory Response Positive Regulation Of Endothelial Cell Apoptotic Process	Monoatomic Ion Transport Protein Transport T Cell Differentiation Monoatomic Ion Transmembrane Transport Intracellular PH Reduction Monoatomic Anion Transmembrane Transport
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653)
Interacting Genes		13 interacting genes: AGTRAP CMTM5 CMTM6 GPR89B HTR6 MAL2 MDM4 NUP205 RNF115 SEC22B SYP THRA TNFRSF14	1 interacting genes: CD160
Entrez ID		11126	51463
HPRD ID		06833	13604
Ensembl ID		ENSG00000117281	ENSG00000188092
Uniprot IDs		O95971 Q6FH89	B7ZAQ6 P0CG08 X5D7G6
PDB IDs		6NG3 6NG9 6NGG 7MSG
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Adaptive Immune Memory Response Activating MHC Class I Receptor Activity Negative Regulation Of CD4-positive, Alpha-beta T Cell Costimulation Negative Regulation Of T Cell Costimulation Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell MHC Class I Receptor Activity Positive Regulation Of Natural Killer Cell Degranulation MHC Class Ib Receptor Activity MHC Class I Protein Complex Binding Positive Regulation Of Natural Killer Cell Cytokine Production Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Negative Regulation Of T Cell Receptor Signaling Pathway Mucosal Immune Response Positive Regulation Of Endothelial Cell Apoptotic Process Organ Or Tissue Specific Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity T Cell Costimulation Positive Regulation Of Regulated Secretory Pathway Regulation Of T Cell Receptor Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Endothelial Cell Apoptotic Process Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Positive Regulation Of Type II Interferon Production Negative Regulation Of Adaptive Immune Response Regulation Of CD4-positive, Alpha-beta T Cell Activation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Exocytosis Defense Response To Gram-negative Bacterium Regulation Of Leukocyte Mediated Cytotoxicity Kinase Binding Regulation Of Type II Interferon Production Regulation Of Alpha-beta T Cell Activation Regulation Of Cytokine Production Involved In Immune Response Regulation Of Regulated Secretory Pathway Side Of Membrane Negative Regulation Of Vasculature Development Positive Regulation Of Lymphocyte Mediated Immunity Negative Regulation Of Angiogenesis Regulation Of Exocytosis Regulation Of Production Of Molecular Mediator Of Immune Response Regulation Of Lymphocyte Mediated Immunity Negative Regulation Of Immune Response Regulation Of Adaptive Immune Response Transmembrane Signaling Receptor Activity
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