CCDC85B and EXOC8

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		CCDC85B	EXOC8
Description		coiled-coil domain containing 85B	exocyst complex component 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytoskeleton Adherens Junction Anchoring Junction	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Projection Perinuclear Region Of Cytoplasm Cell Periphery
	Molecular Function	Protein Binding Delta-catenin Binding	Protein Binding Small GTPase Binding Phosphatidylinositol Binding
	Biological Process	Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription	Mitotic Cytokinesis Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Endosome Organization Intracellular Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Membrane Fission Vesicle Tethering Involved In Exocytosis
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Hip circumference adjusted for BMI ( 34021172)	Hemoglobin concentration ( 27863252)
Interacting Genes		138 interacting genes: AGGF1 AKAP17A AKIRIN2 APEX2 AQP1 ATOSB BEX2 BEX3 BIRC5 C19orf25 C21orf91 C8orf48 CARD9 CATSPERT CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCNK CDK18 CDKN1A CENPP CEP70 CFAP53 CHCHD3 CHLSN COPS4 CWC25 DEPP1 DEUP1 DOK5 DTNB DUSP13B EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FNDC11 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 INO80B KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NIF3L1 NRIP1 NUP54 ODAD4 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RGS8 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SPATA46 SYT17 SYTL4 TASOR2 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF587 ZNF638 ZNF764 ZNF821	88 interacting genes: AIMP2 ANKRD36B ATP23 BEX2 BICRAL BLOC1S2 BLOC1S6 BLZF1 BORCS6 CAPN3 CCDC33 CCDC85B CCHCR1 CDSN CEP57L1 CWF19L2 DMAP1 EFHC2 ELL2 ESS2 EXOC2 FAM217B GOLGA2 GRAMD4 GTF2E2 HGS IHO1 IKZF3 ISY1 ISY1-RAB43 KIAA1217 KIFC3 KRT15 KRT18 KRT19 KRT20 KRT31 KRT34 KRT36 KRT76 LNX1 LZTS1 MARCHF7 MBD3L1 MBIP MIPOL1 MTUS2 MYOZ3 NAB2 NDC80 NUP54 PBX4 PCM1 PRR35 RAB3IL1 RALA RAPGEF3 RINT1 RUSC1 SASH1 SCARA5 SNAPC1 STMN3 SYCE1 SYT17 TADA2A TBC1D22B TCF12 TCF4 TFIP11 TRIM14 TRIM21 TRIM27 TRIM54 ULK1 UQCC2 USHBP1 USP54 VPS16 VPS37B WASHC1 ZC2HC1A ZNF177 ZNF35 ZNF559-ZNF177 ZNF566 ZNF628 ZSCAN4
Entrez ID		11007	149371
HPRD ID		16101	09943
Ensembl ID		ENSG00000175602	ENSG00000116903
Uniprot IDs		Q15834	Q8IYI6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Nuclear Speck Zinc Ion Binding Spindle Pole Spindle Midzone Assembly Keratin Filament Chromatin Organization Regulation Of RNA Metabolic Process	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Protein Binding Supramolecular Fiber Organization Intermediate Filament Organelle Organization Structural Molecule Activity Negative Regulation Of Viral Transcription Cytoskeleton Regulation Of Viral Transcription Regulation Of Post-translational Protein Modification Regulation Of Protein Autoubiquitination Molecular Adaptor Activity Cytoskeleton Organization Identical Protein Binding Phosphatidylinositol 3-kinase Inhibitor Activity Cellular Localization Vesicle-mediated Transport To The Plasma Membrane Regulation Of Lysosome Size BORC Complex Post-mRNA Release Spliceosomal Complex Gamma-tubulin Binding Autophagosome Epidermis Development
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