TOMM34 and IFT52

		TOMM34	IFT52
Description		translocase of outer mitochondrial membrane 34	intraflagellar transport 52
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane	Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Dendrite Terminus Ciliary Tip Ciliary Base Photoreceptor Cell Cilium
	Molecular Function	Protein Binding Heat Shock Protein Binding	Protein Binding
	Biological Process	Protein Targeting To Mitochondrion	Neural Tube Formation Heart Looping Smoothened Signaling Pathway Determination Of Left/right Symmetry Dorsal/ventral Pattern Formation Negative Regulation Of Keratinocyte Proliferation Cell Projection Organization Intraciliary Anterograde Transport Intraciliary Transport Embryonic Digit Morphogenesis Keratinocyte Proliferation Cilium Assembly Regulation Of Protein Processing Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Mean reticulocyte volume ( 32888494)
Interacting Genes		12 interacting genes: ACD ATP6V1D CEBPA DMAP1 HSP90AA1 IFT52 POT1 PRKAA1 RAB11FIP3 TERF1 TINF2 VCP	2 interacting genes: SPINT3 TOMM34
Entrez ID		10953	51098
HPRD ID		11641	12789
Ensembl ID		ENSG00000025772	ENSG00000101052
Uniprot IDs		Q15785	Q9Y366
PDB IDs
Enriched GO Terms of Interacting Partners?		Shelterin Complex Nuclear Telomere Cap Complex Regulation Of Telomere Maintenance Via Telomerase Telomere Capping Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Telomere Maintenance Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Assembly RNA-templated DNA Biosynthetic Process Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Positive Regulation Of DNA Metabolic Process Telomere Organization Positive Regulation Of Cellular Component Organization DNA Metabolic Process Negative Regulation Of Chromosome Organization Organelle Organization Regulation Of Chromosome Organization Regulation Of DNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Nucleoplasm Negative Regulation Of DNA Metabolic Process Protein Localization To Organelle Chromosome Organization Protein-containing Complex Binding Cellular Component Assembly Regulation Of Organelle Organization Chromosome, Telomeric Region Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Nucleic Acid Metabolic Process Nucleobase-containing Compound Biosynthetic Process Macromolecule Biosynthetic Process Inclusion Body Assembly Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding	Serine-type Endopeptidase Inhibitor Activity Protein Targeting To Mitochondrion Establishment Of Protein Localization To Mitochondrion Heat Shock Protein Binding Peptidase Inhibitor Activity
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