POP1 and POP5

Number of citations of the paper that reports this interaction (PubMedID 15096576)
37

Data Source:
HPRD (in vitro)

		POP1	POP5
Description		POP1 ribonuclease P/MRP subunit	POP5 ribonuclease P/MRP subunit
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Extracellular Space Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Ribonuclease P Complex Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal TRNA Processing TRNA Decay	TRNA 5'-leader Removal RRNA Processing TRNA Processing
Pathways		tRNA processing in the nucleus	tRNA processing in the nucleus
Drugs
Diseases
GWAS		Glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)	Chronotype ( 30696823) High light scatter reticulocyte count ( 27863252) Intake of total sugars ( 31005972)
Interacting Genes		10 interacting genes: POP4 POP5 PTEN PYCARD RPP25 RPP30 RPP38 RPP40 USP7 WEE2-AS1	16 interacting genes: CAMK2B CCDC102B CEP44 DCDC2 INCA1 KRT34 KRT40 NDUFAB1 POP1 POP4 REL RPP14 RPP25 TRAF1 UBC USHBP1
Entrez ID		10940	51367
HPRD ID		03923	15158
Ensembl ID		ENSG00000104356	ENSG00000167272
Uniprot IDs		Q96F88 Q99575	Q969H6
PDB IDs		6AHR 6AHU	6AHR 6AHU
Enriched GO Terms of Interacting Partners?		Ribonuclease MRP Complex Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Nucleolar Ribonuclease P Complex TRNA Processing TRNA Metabolic Process Ribonuclease P Complex RRNA Processing RRNA Metabolic Process Nucleolus RNA Processing Nucleoplasm Nucleic Acid Metabolic Process RNA Metabolic Process RNA Binding Nucleobase-containing Compound Metabolic Process Negative Regulation Of Synaptic Vesicle Clustering Ribonuclease MRP Activity Myosin I Binding Regulation Of Protein Stability Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Macromolecule Metabolic Process Nucleus Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity NLRP6 Inflammasome Complex Pyrin Domain Binding Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II PML Body Central Nervous System Myelin Maintenance Negative Regulation Of Protein Phosphorylation Rhythmic Synaptic Transmission Symbiont-mediated Disruption Of Host Cell PML Body AIM2 Inflammasome Complex Myeloid Dendritic Cell Activation Involved In Immune Response Negative Regulation Of Phosphorylation Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Pre-mRNA 5'-splice Site Binding Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Synaptic Vesicle Clustering Regulation Of Establishment Of Protein Localization To Telomere NLRP1 Inflammasome Complex Negative Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Protein Metabolic Process	Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Ribonuclease MRP Complex Ribonuclease P Complex TRNA Processing TRNA Metabolic Process Centriole-centriole Cohesion Structural Molecule Activity Acyl Carrier Activity Structural Constituent Of Skin Epidermis Cytoskeleton
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