RALBP1 and CCDC13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RALBP1	CCDC13
Description		ralA binding protein 1	coiled-coil domain containing 13
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoskeleton Plasma Membrane Membrane Nuclear Body	Cytoplasm Centrosome Cytoskeleton Centriolar Satellite Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activator Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity	Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Receptor-mediated Endocytosis Chemotaxis Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cdc42 Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Positive Regulation Of Mitochondrial Fission Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	DNA Damage Response Cell Projection Organization Cytoplasmic Microtubule Organization Non-motile Cilium Assembly
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)	Clozapine-induced agranulocytosis ( 25187353) Obesity-related traits ( 23251661) Periodontitis (DPAL) ( 24024966)
Interacting Genes		47 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF DLG4 DRC4 FADD GSE1 HOOK2 HSF1 HSPA13 IKBKG ITSN1 KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707	50 interacting genes: ASB15 BTG3 CARD9 CCDC120 CCDC136 CCHCR1 CCND3 CDR2 DISC1 EFHC2 EHHADH ENKD1 FAM161A FAM161B FAM221B FAM90A1 FCHO1 GMCL1 GOLGA2 HAP1 HOMEZ HSF2BP KIAA1328 KRT34 LZTS1 MCRS1 MEOX2 MYF5 NEFL OPTN PIBF1 PRDM16 RALBP1 RPSA TCHP TCL1A TFIP11 TP53BP2 TRAF3 TRIM23 TSGA10IP TXLNB USP54 VPS52 ZBED1 ZBTB22 ZBTB43 ZGPAT ZNF670 ZRANB1
Entrez ID		10928	152206
HPRD ID		09013	08692
Ensembl ID		ENSG00000017797	ENSG00000244607
Uniprot IDs		Q15311	Q8IYE1 Q96LI1
PDB IDs		2KWH 2KWI 2MBG 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macrophage Differentiation Regulation Of Macrophage Differentiation Regulation Of Endocytosis Protein-macromolecule Adaptor Activity Intracellular Signaling Cassette Endocytosis Cellular Component Assembly Protein Binding Intracellular Signal Transduction Positive Regulation Of Immune System Process Regulation Of Vesicle-mediated Transport Cytosol Positive Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Receptor-mediated Endocytosis Protein Kinase Binding Cytoplasmic Microtubule Organization Import Into Cell Death Effector Domain Binding Regulation Of Signal Transduction Centrosome Regulation Of Receptor Internalization Protein-containing Complex Organization Tumor Necrosis Factor Receptor Binding Ripoptosome CD95 Death-inducing Signaling Complex Protein-containing Complex Assembly Cell Death Response To Lipopolysaccharide Death-inducing Signaling Complex Positive Regulation Of Leukocyte Differentiation Ubiquitin Protein Ligase Binding Programmed Cell Death Identical Protein Binding Positive Regulation Of Cellular Component Organization Tumor Necrosis Factor Receptor Superfamily Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Myeloid Cell Differentiation Microtubule Cytoskeleton Organization Regulation Of Canonical NF-kappaB Signal Transduction Organelle Organization Apoptotic Signaling Pathway Positive Regulation Of Peptide Hormone Secretion TRAIL-activated Apoptotic Signaling Pathway Response To Molecule Of Bacterial Origin Positive Regulation Of Signal Transduction Positive Regulation Of Peptide Secretion Cytoskeleton Organization Regulation Of Cytokine Production	Protein Binding Cytoskeleton
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