STARD10 and YIF1A

		STARD10	YIF1A
Description		StAR related lipid transfer domain containing 10	Yip1 interacting factor homolog A, membrane trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Microvillus Cilium Membrane Motile Cilium Cell Projection Intercellular Canaliculus	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Lipid Binding	Protein Binding
	Biological Process	Lipid Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport
Pathways		Synthesis of PC	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Acute insulin response ( 28490609) Alanine aminotransferase levels ( 33547301) Alloimmunization response to red blood cell transfusion in sickle cell anemia ( 25670933) C-reactive protein levels ( 30388399) Crohn's disease ( 23850713) Liver enzyme levels (alanine transaminase) ( 33972514) Mean platelet volume ( 27863252) Mean spheric corpuscular volume ( 32888494) Waist circumference ( 28552196) Waist circumference adjusted for body mass index ( 28552196)	Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		4 interacting genes: APP PRMT6 TP53 YIF1A	82 interacting genes: ADAM17 APOA5 AQP6 ARLN BNIP2 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GNL1 GPR37 GPR42 GPX8 HEATR1 JOSD2 KAT5 KCNK5 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MRPL18 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PRIM1 PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35H1 SLCO2B1 SNX10 SNX11 SNX2 STARD10 STIP1 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 WDR74 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27
Entrez ID		10809	10897
HPRD ID		18116	06755
Ensembl ID		ENSG00000214530	ENSG00000174851
Uniprot IDs		Q9Y365	A6NGW1 A8K509 O95070
PDB IDs		6SER
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression, Epigenetic Protein-folding Chaperone Binding Amyloid-beta Complex Growth Cone Lamellipodium Chromatin Remodeling Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Regulation Of Carbohydrate Catabolic Process Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Regulation Of Proteolysis Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Molecular Function Activator Activity Chromatin Binding Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Cellular Senescence Histone H2AR3 Methyltransferase Activity Regulation Of Mitochondrion Organization Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Central Nervous System Development Chromatin Organization Negative Regulation Of Transcription By RNA Polymerase II Cell Activation Involved In Immune Response Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Pentose-phosphate Shunt Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Proteolysis	Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Protein Binding Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Glutathione Peroxidase Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Regulation Of Mast Cell Apoptotic Process Endoplasmic Reticulum Organization
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