CETN1 and CCP110

Number of citations of the paper that reports this interaction (PubMedID 16760425)
39

Data Source:
BioGRID (biochemical, affinity chromatography technology, pull down)

		CETN1	CCP110
Description		centrin 1	centriolar coiled-coil protein 110
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Cell Projection	Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Protein-containing Complex Cell Projection
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Centriole Replication Cellular Response To Heat Cell Division	Centriole Replication Cell Projection Organization Ciliary Basal Body Organization Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Centrosome Duplication Negative Regulation Of Cilium Assembly
Pathways		Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Ub-specific processing proteases AURKA Activation by TPX2 RHOV GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: CCP110 POC5 PRKACA SGSM1	15 interacting genes: AKAP9 CALM1 CALM3 CDK1 CDK2 CEP97 CETN1 CETN2 DCAF1 ELOB PCNT PNMA1 TFIP11 USP33 USP7
Entrez ID		1068	9738
HPRD ID		04425	10848
Ensembl ID		ENSG00000177143	ENSG00000103540
Uniprot IDs		A0A140VJG3 Q12798	O43303
PDB IDs
Enriched GO Terms of Interacting Partners?		CAMP-dependent Protein Kinase Complex Protein-lipid Complex Assembly Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Cardiac Conduction Vascular Endothelial Cell Response To Fluid Shear Stress Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Glycolytic Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Cellular Response To Glucagon Stimulus Centrosome Negative Regulation Of Interleukin-2 Production Response To Laminar Fluid Shear Stress Sperm Capacitation CAMP-dependent Protein Kinase Activity Interleukin-2-mediated Signaling Pathway Calcium Channel Complex Cellular Response To Laminar Fluid Shear Stress Negative Regulation Of ATP Metabolic Process Plasma Lipoprotein Particle Assembly Regulation Of Bicellular Tight Junction Assembly Cellular Response To Epinephrine Stimulus Multicellular Organismal-level Water Homeostasis Positive Regulation Of Cholesterol Biosynthetic Process Cell Communication By Electrical Coupling High-density Lipoprotein Particle Assembly Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Renal Water Homeostasis Response To Parathyroid Hormone Positive Regulation Of Gluconeogenesis Response To Glucagon Positive Regulation Of Protein Export From Nucleus Cellular Response To Cold Cell Communication By Electrical Coupling Involved In Cardiac Conduction Protein Localization To Lipid Droplet Cilium Intracellular Potassium Ion Homeostasis Protein Kinase A Regulatory Subunit Binding Mitochondrial Protein Catabolic Process Response To Epinephrine CAMP/PKA Signal Transduction Nucleotide-activated Protein Kinase Complex Channel Activator Activity Cell Communication Involved In Cardiac Conduction Regulation Of Cell Cycle Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Negative Regulation Of Cilium Assembly Centriole Centriole Replication Centrosome Duplication Ciliary Basal Body Organization	Centrosome Cytoskeleton G2/M Transition Of Mitotic Cell Cycle Cell Cycle G2/M Phase Transition Negative Regulation Of High Voltage-gated Calcium Channel Activity Microtubule Organizing Center Organization Centriole Replication Cytoplasm Regulation Of Cardiac Muscle Cell Action Potential Cyclin-dependent Protein Kinase Activity Centriole Assembly VCB Complex Mitotic Cell Cycle Phase Transition Spindle Microtubule Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Cell Cycle Phase Transition Histone Kinase Activity Centriole Protection From Non-homologous End Joining At Telomere Heterotrimeric G-protein Binding Regulation Of Action Potential Negative Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Cell Cycle Process DNA Metabolic Process Microtubule Cytoskeleton Organization Microtubule-based Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Voltage-gated Potassium Channel Complex Post-translational Protein Modification Titin Binding Regulation Of Cytokinesis Telomere Maintenance In Response To DNA Damage Regulation Of Voltage-gated Calcium Channel Activity Detection Of Calcium Ion Organelle Organization Microtubule Organizing Center Protein Deubiquitination Regulation Of Cell Communication By Electrical Coupling Regulation Of Heart Rate Protein Phosphatase Activator Activity Calyx Of Held Centrosome Duplication Protein Modification By Small Protein Removal G-protein Beta/gamma-subunit Complex Binding Regulation Of Cell Cycle Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
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