GAS2L1 and GPSM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GAS2L1	GPSM2
Description		growth arrest specific 2 like 1	G protein signaling modulator 2
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytoskeleton Microtubule Actin Filament Microtubule Plus-end	Spindle Pole Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Membrane Lateral Plasma Membrane Protein-containing Complex Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region
	Molecular Function	Protein Binding Microtubule Binding Cytoskeletal Anchor Activity Actin Filament Binding	Nucleotide Binding G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding Protein Domain Specific Binding GTPase Regulator Activity Identical Protein Binding Dynein Complex Binding
	Biological Process	Microtubule Bundle Formation Negative Regulation Of Microtubule Depolymerization Cellular Response To Starvation Regulation Of Microtubule Polymerization Or Depolymerization Actin Crosslink Formation Protein Localization To Microtubule Plus-end	Establishment Of Mitotic Spindle Orientation Mitotic Spindle Organization G Protein-coupled Receptor Signaling Pathway Response To Light Intensity Cell Division Maintenance Of Centrosome Location Regulation Of Mitotic Spindle Organization Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Spindle Assembly
Pathways			G alpha (i) signalling events
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Pancreatic cancer ( 25086665)	Fat distribution (HIV) ( 21897333)
Interacting Genes		2 interacting genes: GPSM2 POT1	18 interacting genes: AGR2 ARHGEF40 CLCC1 DLG4 FXR1 FXR2 GAS2L1 GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC LRRC8E NRIP1 NUMA1 WHRN
Entrez ID		10634	29899
HPRD ID		03676	06609
Ensembl ID		ENSG00000185340	ENSG00000121957
Uniprot IDs		A0A5E8 Q99501	B4DIF1 P81274
PDB IDs			3SF4 4WND 4WNE 4WNF 4WNG 5A6C 6HC2
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Telomeric Loop Disassembly 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Positive Regulation Of DNA Strand Elongation Telomeric D-loop Binding Telomere Assembly Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Cell Cortex Region Lateral Cell Cortex Single-stranded Telomeric DNA Binding Telomerase Inhibitor Activity Nuclear Telomere Cap Complex Shelterin Complex Telomeric D-loop Disassembly Positive Regulation Of Organelle Organization DEAD/H-box RNA Helicase Binding Establishment Of Protein Localization To Telomere Positive Regulation Of Spindle Assembly Regulation Of Protein Localization To Cell Cortex Maintenance Of Centrosome Location Positive Regulation Of Protein Localization To Cell Cortex G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Telomere Capping Regulation Of DNA Strand Elongation Response To Light Intensity GDP-dissociation Inhibitor Activity Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Negative Regulation Of Telomere Maintenance Via Telomerase Dynein Complex Binding Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening GTPase Regulator Activity Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane G-protein Alpha-subunit Binding Regulation Of Spindle Assembly Centrosome Localization Positive Regulation Of Cellular Component Organization Mitotic Spindle Pole Establishment Of Mitotic Spindle Orientation Negative Regulation Of Telomere Maintenance	Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Regulation Of Long-term Neuronal Synaptic Plasticity Heterotrimeric G-protein Complex Regulation Of Neuronal Synaptic Plasticity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Adenylate Cyclase Regulator Activity Modulation Of Chemical Synaptic Transmission GTPase Activity Ciliary Basal Body Positive Regulation Of Protein Localization To Cell Cortex Regulation Of Protein Localization To Cell Periphery GTP Binding Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Long-term Neuronal Synaptic Plasticity Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Regulation Of Synaptic Plasticity G Protein Activity G Protein-coupled Receptor Binding GDP Binding Positive Regulation Of Protein Localization To Cell Periphery Cell Division Regulation Of Biological Quality Dendrite Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Translation Regulator Activity Regulation Of Cell Communication Regulation Of Signaling G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of Protein Localization Cytoskeletal Anchor Activity Cytoplasm Microtubule Plus-end Dentate Gyrus Development Neuron Projection Negative Regulation Of Secretion By Cell Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Secretion P2Y1 Nucleotide Receptor Binding Negative Regulation Of Transport Cell Cortex Negative Regulation Of Insulin Secretion Positive Regulation Of Metabolic Process Regulation Of Mitotic Spindle Organization Midbody Positive Regulation Of Protein Localization Negative Regulation Of Peptide Secretion
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